NCT06346067 2026-02-27A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)Erasca, Inc.Phase 3 Active not recruiting78 enrolled
NCT02224781 2026-02-18Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 MelanomaNational Cancer Institute (NCI)Phase 3 Active not recruiting267 enrolled 8 charts
NCT01584648 2021-02-17A Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant MelanomaNovartisPhase 3 Completed423 enrolled 15 charts
NCT01245062 2018-04-05GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive MelanomaGlaxoSmithKlinePhase 3 Completed322 enrolled 24 charts