Clinical Trials

Phase 3 Active not recruiting

Uterine Cervical Neoplasms

NCT05059522 2026-04-14

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

68 enrolled

Ovarian Neoplasms

NCT07418749 2026-04-06

A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer

Phase 3 Recruiting

398 enrolled

502 enrolled 18 charts 2 FDA

Uterine Cervical Neoplasms

NCT04697628 2026-02-24

innovaTV 301

Phase 3 Completed

Uterine Cervical Neoplasms

NCT03875144 2026-02-09

MESOTIP

Phase 2 Suspended

66 enrolled

Phase 2 Active not recruiting

Peritoneal Neoplasms

NCT06630325 2026-01-07

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

30 enrolled

GastrointestinalGenitourinaryGynecologic

Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT04956640 2025-09-25

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Phase 1/2 Recruiting

540 enrolled

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT04680988 2025-08-05

A Study of SHR-1210± SHR-1020 Versus Chemotherapy in Patients With Recurrent or Metastatic Cervical Cancer

194 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Uterine Cervical Neoplasms, Recurrence

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT02922764 2025-03-26

A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer

146 enrolled

GynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT02489903 2025-03-17

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

EndocrineGynecologicNETThoracic

139 enrolled 14 charts

Carcinoma, Ovarian Epithelial, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Carcinoma, Small Cell, Neuroendocrine Tumors

NCT06758557 2025-01-23

A Study to Evaluate the Safety and Efficacy of HB0025 Injection in Patients With Advanced Solid Tumor

Phase 1/2 Recruiting

282 enrolled

Endometrial Neoplasms

NCT01001910 2024-02-28

Pemetrexed and Carboplatin in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

22 enrolled 11 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT04943627 2022-10-05

Balstilimab Versus Investigator Choice Chemotherapy in Patients With Recurrent Cervical Cancer (BRAVA)

Phase 3 Withdrawn

Uterine Cervical Neoplasms

NCT03023319 2022-06-14

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

GenitourinaryGynecologicOther solid neoplasmThoracic

6 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Mesothelioma, Ovarian Neoplasms, Thymoma, Thymus Neoplasms

NCT00230542 2018-08-13

Carboplatin and Pemetrexed in Recurrent Platinum Sensitive Ovarian Cancer

44 enrolled

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00096187 2018-04-12

Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Low-Risk Gestational Trophoblastic Tumor After a Molar Pregnancy

Phase 2 Terminated

55 enrolled

Gestational Trophoblastic Disease

NCT00691301 2018-01-09

Pemetrexed and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer

55 enrolled 10 charts

Uterine Cervical Neoplasms

NCT00702299 2016-01-01

Alimta® Plus Cisplatin & Paclitaxel Given Intraperitonelly; First Line Tx Stage III Ovarian Cancer

15 enrolled 12 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01172028 2015-12-03

Pemetrexed Disodium and Docetaxel in Treating Patients With Advanced Solid Tumors

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

33 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male

NCT00868192 2014-10-20

Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian Primary Peritoneal Carcinoma

38 enrolled 17 charts

Ovarian Neoplasms

NCT00087087 2014-02-14

Pemetrexed Disodium in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

51 enrolled

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00087100 2014-02-14

Pemetrexed Disodium in Treating Patients With Persistent or Recurrent Endometrial Cancer

51 enrolled

Endometrial Neoplasms

NCT00087113 2014-02-14

Pemetrexed Disodium in Treating Patients With Recurrent Cancer of the Cervix

Uterine Cervical Neoplasms

NCT00489359 2011-06-16

Trial of Pemetrexed and Carboplatin in Patients With Recurrent Ovarian or Primary Peritoneal Cancer

Phase 1/2 Completed

86 enrolled 23 charts

Ovarian Neoplasms

NCT00461786 2009-12-04

A Study of Single Agent Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer

51 enrolled 15 charts

Ovarian Neoplasms

NCT00190983 2009-11-20

A Trial for Patients With Advanced/Recurrent Cervical Cancer

29 enrolled 14 charts

Uterine Cervical Dysplasia, Genital Neoplasms, Female, Uterine Neoplasms

NCT00377520 2009-11-20

A Trial for Patients With Advanced/Recurrent Endometrial Cancer

27 enrolled 10 charts

Genital Neoplasms, Female, Neoplasms, Neoplasms by Site, Urogenital Neoplasms, Uterine Neoplasms, Endometrial Neoplasms

NCT00315861 2009-01-23

Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies

15 enrolled

GynecologicThoracic

Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00190918 2007-08-09

A Trial for Patients With Gestational Trophoblastic Disease

50 enrolled

Choriocarcinoma, Hydatidiform Mole, Trophoblastic Neoplasms, Uterine Neoplasms

NCT00109096 2007-05-17

Study of Pemetrexed in the Treatment of Patients With Ovarian Cancer Who Have Failed Prior Platinum-Based Chemotherapy

100 enrolled

Ovarian Neoplasms

NCT00055432 2006-09-15

Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer

Phase 2 Terminated