Clinical Trials

63 enrolled

Childhood Solid Tumor

NCT04469530 2026-02-27

AflacST1903

Phase 2 Recruiting

55 enrolled

Solid Tumor

NCT06885697 2026-02-17

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

GastrointestinalGynecologicOther solid neoplasmThoracic

100 enrolled

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT06556108 2026-01-20

ALPP CAR-T Cells for ALPP-Positive Advanced Solid Tumors

Phase 1/2 Completed

5 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Advanced Solid Tumors

NCT07342738 2026-01-15

TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors

25 enrolled

Phase 2 Active not recruiting

KRAS G12V

NCT02870907 2026-01-07

RB SFCE 09

195 enrolled

Other solid neoplasmThoracic

Retinoblastoma

NCT05380713 2025-12-29

......SMARTEST Trial......

Phase 2 Completed

30 enrolled

Mesothelioma, Malignant

NCT06241456 2025-12-09

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

351 enrolled

Advanced Solid Tumor

NCT02414269 2025-10-08

Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin

BreastOther solid neoplasmThoracic

113 enrolled

Breast Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis

NCT00186888 2025-09-04

Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

Phase 3 Completed

107 enrolled 34 charts

Eye Neoplasms, Retinoblastoma, Retinal Neoplasms

NCT03907852 2025-08-27

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

GastrointestinalGynecologicOther solid neoplasmThoracic

57 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Mesothelioma, Ovarian Neoplasms, Cholangiocarcinoma

NCT05451849 2025-08-27

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

BreastGastrointestinalGynecologicOther solid neoplasmThoracic

6 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT05279300 2025-08-11

A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas

LymphoidOther solid neoplasm

480 enrolled

Advanced Solid Tumor

NCT02498912 2025-07-31

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Phase 1 Active not recruiting

18 enrolled

Phase 1 Active not recruiting

Solid Tumors

NCT04577326 2025-07-25

Mesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma

14 enrolled

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT05275777 2025-07-25

A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer

BreastOther solid neoplasm

66 enrolled

HER2-negative Breast Cancer

NCT05881525 2025-07-16

NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors

18 enrolled

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

Advanced Solid Tumors

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Phase 2 Recruiting

240 enrolled

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT07010523 2025-06-08

Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Phase NA Recruiting

24 enrolled