Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Kidney Neoplasms, Melanoma, Mesothelioma

NCT07170592 2026-04-07

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients

Phase 1 Not yet recruiting

24 enrolled

Other solid neoplasm

Treatment-Refractory Solid Tumors

Clinical Trials

A Study of NB004 as Monotherapy or Combination Therapy in Patients With Advanced Solid Tumors

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

SUMMIT-1

Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

TLN-372 in Advanced KRAS Mutant Solid Tumors

A Study of BGM-2121 in Patients With Advanced Solid Tumors

A Phase I Clinical Study of HLX316 in Participants With Advanced/Metastatic Solid Tumors

MYTHIC

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

A Study of HS-20110 in Participants With Advanced Solid Tumors

A Study of HDM2024 in Participants With Advanced Solid Tumors

Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

A First-in-Human Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors

A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

A Clinical Study on the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-1049 in Patients With Advanced Solid Tumors

A Phase I Clinical Study of HLX3902 in Patients With mCRPC and Other Advanced Tumours

CLINCH

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

A Study of BG-C477 in Participants With Advanced Solid Tumors

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors

A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

GT101 Injection for the Treatment of Metastatic or Recurrent Solid Tumors

SNV1521 in Participants With Advanced Solid Tumors

A Study of BL-M08D1 in Patients With Locally Advanced or Metastatic Solid Tumors

To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors

Study of TRX-920 for Patients With Advanced Solid Tumors

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors

A Trial to Investigate the Safety of E303 in Participants With Advanced Refractory Solid Tumors

A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion

Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacokinetics, and Preliminary Efficacy of FS-8002

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

HF158K1 in Patients With HER-2 Expressing Advanced Solid Tumors

STEALTH-001

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients