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NCT04396860 2026-04-22

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Phase 2/3 Completed

159 enrolled 17 charts

Gliosarcoma

NCT02180867 2026-04-13

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Phase 2/3 Active not recruiting

140 enrolled 22 charts

Plasma cellSarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Granuloma, Plasma Cell, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Chondrosarcoma, Mesenchymal, Dermatofibrosarcoma, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Perivascular Epithelioid Cell Neoplasms

NCT02306161 2026-04-13

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Phase 3 Active not recruiting

312 enrolled 14 charts

Sarcoma, Ewing

NCT02567435 2026-04-13

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Phase 3 Active not recruiting

325 enrolled 14 charts

Rhabdomyosarcoma, Rhabdomyosarcoma, Alveolar, Rhabdomyosarcoma, Embryonal

NCT03197506 2026-03-25

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Phase 2 Active not recruiting

52 enrolled 19 charts

Glioblastoma, Gliosarcoma

NCT03217266 2025-09-23

Navtemadlin and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma

Phase 1 Completed

39 enrolled 27 charts

Sarcoma

NCT03150862 2025-02-04

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Completed

116 enrolled 31 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Nervous System Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Gliosarcoma

NCT03338959 2024-07-23

Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma

Phase 1/2 Completed

27 enrolled 10 charts

Sarcoma

NCT01922076 2024-01-31

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Phase 1 Completed

46 enrolled 20 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Gliosarcoma

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02573324 2023-05-11

Intellance1

Phase 3 Completed

691 enrolled 28 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT03595228 2023-04-14

BN Brachyury and Radiation in Chordoma

Phase 2 Completed

29 enrolled 20 charts

Chordoma

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00354835 2023-01-31

Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

481 enrolled 21 charts

Rhabdomyosarcoma, Sarcoma

NCT00075582 2021-11-19

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Phase 3 Completed

390 enrolled 14 charts

Rhabdomyosarcoma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

122 enrolled 11 charts

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01886105 2019-10-29

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Phase 2 Terminated

4 enrolled 9 charts

Bone Neoplasms, Sarcoma, Osteosarcoma

NCT00486603 2019-07-10

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

92 enrolled 18 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01977677 2018-10-23

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

Phase 1/2 Completed

30 enrolled 11 charts

Glioblastoma, Glioma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00089544 2018-04-13

Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

Phase 2 Terminated

23 enrolled 6 charts

Sarcoma

NCT00085254 2016-02-25

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

112 enrolled 14 charts

Glioblastoma, Gliosarcoma

NCT00004146 2015-05-08

Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM

Phase 2 Completed

55 enrolled 10 charts

Glioblastoma, Gliosarcoma

NCT00042991 2014-05-28

Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas

Phase 1/2 Completed

69 enrolled 27 charts

Untreated Childhood Anaplastic Astrocytoma