Clinical Trials Browser

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NCT05843253 2026-04-22

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Phase 2 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT07544992 2026-04-22

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Phase 1 Not yet recruiting

Astrocytoma, Glioblastoma

NCT07462507 2026-04-21

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT05698524 2026-04-17

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

Phase 1 Recruiting

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02800486 2026-04-13

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Phase 1 Recruiting

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Phase 1/2 Not yet recruiting

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07089641 2026-04-07

ERAS801-SARG

Phase 1 Recruiting

Astrocytoma

NCT05789394 2026-04-02

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy

Phase 1 Recruiting

Astrocytoma, Glioblastoma

NCT07417761 2026-04-02

TUVASTRAT

Phase 2 Recruiting

Astrocytoma

NCT05839379 2026-03-31

Targeted Pediatric High-Grade Glioma Therapy

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03596086 2026-03-30

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Phase 1/2 Recruiting

Astrocytoma, Glioblastoma

NCT03603405 2026-03-30

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

Phase 1/2 Recruiting

Astrocytoma, Glioblastoma

NCT04197934 2026-03-30

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Phase 1 Active not recruiting

Astrocytoma, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Lung Neoplasms

NCT03796273 2026-03-20

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

Phase EARLY_PHASE1 Terminated

Astrocytoma, Glioma, Oligodendroglioma

NCT05577416 2026-03-18

AB-218-IIT-201

Phase EARLY_PHASE1 Completed

Astrocytoma, Glioma, Oligodendroglioma

NCT05393258 2026-03-17

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

Phase NA Completed

Astrocytoma, Glioma, Oligodendroglioma

NCT06333899 2026-03-12

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Phase EARLY_PHASE1 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT03896568 2026-03-05

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Recruiting

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT03152318 2026-03-04

rQNestin

Phase 1 Active not recruiting

Astrocytoma, Brain Neoplasms, Disease, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma

NCT07448480 2026-03-04

GLIOTARG

Active not recruiting

Astrocytoma, Glioblastoma, Glioma

NCT06665724 2026-02-27

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Phase 1 Completed

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT07439172 2026-02-27

PRC

Phase 2 Not yet recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT05345002 2026-02-20

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Phase 2 Recruiting

Astrocytoma, Glioma, Oligodendroglioma

NCT03450850 2026-02-17

Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma

Phase NA Completed

1 enrolled 9 charts

Astrocytoma

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Phase NA Recruiting

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT04923126 2026-02-04

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Phase 1/2 Recruiting

Astrocytoma, Ganglioneuroma, Oligodendroglioma, Neoplasms, Neuroepithelial, Ganglioglioma, Neurocytoma

NCT05683808 2026-01-30

VTE-POG

Phase 2 Recruiting

CNSClassical hematology

Astrocytoma, Glioblastoma, Glioma, Venous Thromboembolism