NCT02250755 2026-04-22
METAPERF
University Hospital, Lille
Phase NA Completed
Clinical Trials
1,360 trialsNCT04192981 2026-04-22
GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center
Phase 1 Active not recruiting
NCT04689048 2026-04-22
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
Baptist Health South Florida
Phase 1 Recruiting
NCT05366179 2026-04-22
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
UNC Lineberger Comprehensive Cancer Center
Phase 1 Recruiting
NCT05843253 2026-04-22
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Nationwide Children's Hospital
Phase 2 Recruiting
NCT04114981 2026-04-21
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
Alliance for Clinical Trials in Oncology
Phase 3 Active not recruiting
NCT06636162 2026-04-21
Window of Opportunity Study of DSP-0390 in Gliomas
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT07462507 2026-04-21
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Washington University School of Medicine
Phase 2 Recruiting
NCT07542288 2026-04-21
Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases:
The Second Affiliated Hospital of Hainan Medical University
Phase 2/3 Not yet recruiting
NCT03684109 2026-04-20
Non-invasive Glioma Characterization Through Molecular Imaging
University of Miami
Phase NA Recruiting
NCT06796543 2026-04-20
TARGET-RT
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase NA Recruiting
NCT07539753 2026-04-20
Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases
Nanfang Hospital, Southern Medical University
Phase 2 Not yet recruiting
NCT02792582 2026-04-17
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
St. Jude Children's Research Hospital
Phase 2 Active not recruiting
NCT03163368 2026-04-17
Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors
Cedars-Sinai Medical Center
Phase EARLY_PHASE1 Active not recruiting
NCT06466031 2026-04-17
TYR-GLIO
Copernicus Memorial Hospital
Phase NA Recruiting
NCT07224503 2026-04-17
C-SMART vs BE Well for Patients With Brain Tumors
Virginia Commonwealth University
Phase NA Recruiting
NCT02645487 2026-04-16
SRS
University of Texas Southwestern Medical Center
Phase NA Active not recruiting
NCT03122197 2026-04-16
Study of Letrozole in Recurrent Gliomas
University of Cincinnati
Phase EARLY_PHASE1 Recruiting
NCT05013892 2026-04-16
NTS-WBRT in Brain Metastases
Massachusetts General Hospital
Phase 2 Recruiting
NCT05064280 2026-04-16
Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases
M.D. Anderson Cancer Center
Phase 2 Recruiting
NCT00814021 2026-04-15
Sunitinib in Treating Patients With Kidney Cancer That Has Spread to the Brain
Institut Claudius Regaud
Phase 2 Completed
NCT02693990 2026-04-15
A Trial of Increased Dose Intensity Modulated Proton Therapy (IMPT) for High-Grade Meningiomas
Massachusetts General Hospital
Phase NA Active not recruiting
NCT03175432 2026-04-15
Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT03286335 2026-04-15
Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
Massachusetts General Hospital
Phase NA Recruiting
NCT05047913 2026-04-15
Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Active not recruiting
NCT06015295 2026-04-15
A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for Detecting True-versus Pseudo-Progression of Brain Metastases on Immunotherapy
M.D. Anderson Cancer Center
Phase NA Recruiting
NCT06649058 2026-04-15
EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active
M.D. Anderson Cancer Center
Phase 2 Recruiting
NCT06666712 2026-04-15
TPT CED rHGG
Columbia University
Phase 1 Recruiting
NCT07530536 2026-04-15
rTMS for Postoperative Brain Tumor Patients
Columbia University
Phase NA Recruiting
NCT02800486 2026-04-13
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
Northwell Health
Phase 2 Recruiting
NCT03115398 2026-04-13
A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery
Montefiore Medical Center
Phase NA Completed
NCT03911388 2026-04-13
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT03994796 2026-04-13
Genetic Testing in Guiding Treatment for Patients With Brain Metastases
Alliance for Clinical Trials in Oncology
Phase 2 Active not recruiting
NCT04185038 2026-04-13
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
Seattle Children's Hospital
Phase 1 Recruiting
NCT05222620 2026-04-13
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
Mayo Clinic
Phase 2 Recruiting
NCT06599879 2026-04-13
IPANEMA
Institut Claudius Regaud
Phase NA Recruiting
NCT07505979 2026-04-13
SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases
National Taiwan University Hospital
Phase 2 Not yet recruiting
NCT03277638 2026-04-09
Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)
Case Comprehensive Cancer Center
Phase 1/2 Active not recruiting
NCT05048212 2026-04-09
A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases
M.D. Anderson Cancer Center
Phase 2 Recruiting
NCT06238882 2026-04-09
Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.
Instituto Nacional de Cancerologia de Mexico
Phase NA Recruiting
NCT06282874 2026-04-09
Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases
Guangdong Association of Clinical Trials
Phase 4 Active not recruiting
NCT07134842 2026-04-09
WinGlio-ipi
University College, London
Phase 1 Recruiting
NCT07520370 2026-04-09
Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor
Beijing Tiantan Hospital
Phase NA Not yet recruiting
NCT05987644 2026-04-08
DURABLE
Hoosier Cancer Research Network
Phase 1/2 Recruiting
NCT07206849 2026-04-08
Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)
Nationwide Children's Hospital
Phase 2 Not yet recruiting
NCT07248228 2026-04-08
Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)
Case Comprehensive Cancer Center
Phase 2 Not yet recruiting
NCT07383649 2026-04-08
Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection
The Methodist Hospital Research Institute
Phase 2 Recruiting
NCT07512154 2026-04-07
Precision Radiotherapy Enabled by Molecular MRI
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase NA Not yet recruiting
NCT05703269 2026-04-06
HYPOGRYPHE
Wake Forest University Health Sciences
Phase NA Active not recruiting
NCT05704933 2026-04-06
Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute
Phase EARLY_PHASE1 Completed