Clinical Trials

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT05519865 2026-04-20

A Study of Tucidinostat Combined With Tislelizumab as First-line Treatment in Advanced NSCLC

118 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03881488 2026-04-17

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

DermatologicHead & NeckOther solid neoplasmThoracic

100 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Melanoma, Mesothelioma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT03634241 2026-04-16

Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study

45 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04479306 2026-04-16

Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

37 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01630733 2026-04-15

ENSPIRIT

664 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT01118676 2026-04-14

Cilengitide Together With Radiochemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer

14 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01352962 2026-04-14

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

GastrointestinalGenitourinaryGynecologicThoracic

18 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT03446547 2026-04-14

ASTEROID

106 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05826366 2026-04-14

Imfinzi/Imjudo NSCLC Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - CEI/SCEI

296 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07526961 2026-04-14

Real-World Outcomes of First-Line Nivolumab + Ipilimumab With Chemotherapy in Non-Small Cell Lung Cancer in Poland

240 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05106374 2026-04-13

Risk of Chemotherapy Toxicity in Older Patients With Blood Cancer or Non-small Cell Lung Cancer

Other hematologic neoplasmThoracic

182 enrolled

Carcinoma, Non-Small-Cell Lung, Hematologic Neoplasms

NCT05461430 2026-04-13

TraveraRTGx

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

72 enrolled

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT03236935 2026-04-09

Phase Ib of L-NMMA and Pembrolizumab

DermatologicHead & NeckThoracic

12 enrolled 15 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, DNA Repair-Deficiency Disorders

NCT03523702 2026-04-09

SPRINT

25 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT06159790 2026-04-09

A Study to Compare Efficacy, Safety, and Immunogenicity of GME751 and EU-authorized Keytruda in Adult Participants With Untreated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)

218 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05077709 2026-04-08

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

63 enrolled 18 charts

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung

NCT05110196 2026-04-07

Study of Capmatinib in Indian Patients With MET Exon 14 Skipping Mutation Positive Advanced NSCLC.

Phase 4 Completed

50 enrolled

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07143513 2026-04-07

Real World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer Patients

102 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01167530 2026-04-06

RAD001

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02087423 2026-04-06

ATLANTIC

446 enrolled 23 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03158129 2026-04-06

Nivolumab With or Without Ipilimumab or Chemotherapy in Treating Patients With Previously Untreated Stage I-IIIA Non-small Cell Lung Cancer

101 enrolled 19 charts

Carcinoma, Non-Small-Cell Lung

NCT05387512 2026-04-06

Real-world Association Between Concomitant Beta-blocker Exposure and Anti-PD-1/PD-L1 Treatment Outcomes in Advanced Non-Small Cell Lung Cancer

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03589547 2026-04-02

358

11 enrolled

Phase EARLY_PHASE1 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03744468 2026-04-02

Study of Surzebiclimab (BGB-A425) and Alcestobart (LBL-007) in Combination With Tislelizumab in Advanced Solid Tumors

Phase 1/2 Completed

147 enrolled 74 charts

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung

NCT05873439 2026-04-01

Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC

3 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04677595 2026-03-31

GeoMETry-C

36 enrolled 26 charts

Carcinoma, Non-Small-Cell Lung

NCT03678350 2026-03-27

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Other solid neoplasmThoracic

9 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT04351256 2026-03-27

TRADE-hypo

51 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03915951 2026-03-24

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

98 enrolled 18 charts 2 FDA

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT04484142 2026-03-24

Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

137 enrolled 9 charts 2 FDA

Carcinoma, Non-Small-Cell Lung

NCT07490639 2026-03-24

FSPC-LC

Phase NA Completed

110 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04960059 2026-03-19

NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

DermatologicGenitourinaryThoracic

24 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms

NCT07475637 2026-03-19

LBM-T790M

70 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02973789 2026-03-18

Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

291 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT04143711 2026-03-18

Study of DF1001 in Patients With Advanced Solid Tumors

Phase 1/2 Completed

270 enrolled

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04423029 2026-03-18

A Study of DF6002 Alone and in Combination With Nivolumab

170 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT06108479 2026-03-18

Study of DF6215 in Patients With Advanced Solid Tumors

DermatologicGenitourinaryGynecologicHead & NeckThoracic

35 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms

NCT02504372 2026-03-17

PEARLS

1,177 enrolled 21 charts 2 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT02818920 2026-03-17

TOP 1501

35 enrolled 11 charts

Phase EARLY_PHASE1 Completed

Carcinoma, Non-Small-Cell Lung

NCT04298606 2026-03-17

A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pneumonia, Pulmonary Disease, Chronic Obstructive

NCT04609566 2026-03-16

Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors

DermatologicHead & NeckThoracic

161 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT06894771 2026-03-16

MK-4700-001

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

5 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasms, Triple Negative Breast Neoplasms

NCT01647867 2026-03-13

MetLung

Phase NA Completed

56 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02448758 2026-03-13

CB(NPC)²

518 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06525246 2026-03-13

Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer

78 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03313804 2026-03-11

Priming Immunotherapy in Advanced Disease With Radiation

76 enrolled 9 charts

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung

NCT06282991 2026-03-10

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled

73 enrolled 12 charts