Clinical Trials

190 enrolled

Colorectal Neoplasms

NCT07222800 2026-04-21

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

800 enrolled

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT05239741 2026-04-17

MK-3475-C66

100 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT07284849 2026-04-16

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

700 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT06662786 2026-04-13

OrigAMI-2

1,000 enrolled

Colorectal Neoplasms

NCT06750094 2026-04-13

OrigAMI-3

700 enrolled

Phase 3 Not yet recruiting

Colorectal Neoplasms

NCT07525206 2026-04-13

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

700 enrolled

Colorectal Neoplasms

NCT05253651 2026-04-07

MOUNTAINEER-03

400 enrolled

Colorectal Neoplasms

NCT07228832 2026-04-06

HARMONi-GI3

600 enrolled

Colorectal Neoplasms

NCT06252649 2026-04-02

CodeBreaK 301

450 enrolled

Neoplasms, Colorectal Neoplasms

NCT06497985 2026-03-19

A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients

430 enrolled

Colorectal Neoplasms

NCT03362177 2026-02-11

RECITE

165 enrolled 22 charts

Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05198934 2026-02-06

CodeBreak300

160 enrolled 2 FDA

Colorectal Neoplasms

NCT04776148 2026-02-05

MK-7902-017

563 enrolled 32 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT04854668 2026-01-30

A Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy as First-line Treatment in Subjects With RAS/BRAF Wild Metastatic Colorectal Cancer

748 enrolled

Colorectal Neoplasms

NCT07361003 2026-01-22

A Phase Ib/III Study of Suvemcitug Plus FTD/TPI in Participants With Refractory Metastatic Colorectal Cancer

464 enrolled

Colorectal Neoplasms

NCT03869892 2025-12-22

SOLSTICE

856 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT04835142 2025-12-05

Comparison of A140 and Erbitux Combined With mfolfox6 to Evaluate Efficacy and Safety of First-line Treatment for Ras Wild-type mCRC

688 enrolled

Colorectal Neoplasms

NCT05600309 2025-11-26

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)-China Extension Study

94 enrolled 15 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT05425940 2025-10-23

STELLAR-303

901 enrolled

Colorectal Neoplasms

NCT04008030 2025-10-03

CheckMate 8HW

839 enrolled 22 charts 2 FDA

Colorectal Neoplasms

NCT05064059 2025-09-17

MK-4280A-007

441 enrolled 24 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT06614192 2025-08-26

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

460 enrolled

Phase 3 Not yet recruiting

Colorectal Neoplasms

NCT07134205 2025-08-21

The Study of JMT101 Combined With Irinotecan as a ≥3rd-Line Treatment in Metastatic Colorectal Cancer

252 enrolled

Colorectal Neoplasms

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

831 enrolled 4 FDA

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT05328908 2025-08-13

RELATIVITY-123

Phase 3 Terminated

770 enrolled

Phase 3 Not yet recruiting

Spinocerebellar Degenerations, Colorectal Neoplasms

NCT07025239 2025-06-17

QL1706 Injection Plus Bevacizumab and XELOX vs Placebo Plus Bevacizumab and XELOX as First-Line Treatment of Unresectable Metastatic Colorectal Cancer

430 enrolled

Colorectal Neoplasms

NCT03206151 2025-05-23

CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer

520 enrolled

Colorectal Neoplasms

NCT04322539 2025-04-04

FRESCO-2

691 enrolled 26 charts 2 FDA

Colonic Neoplasms, Colorectal Neoplasms

NCT04793958 2025-02-11

KRYSTAL-10

461 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03511963 2024-12-31

A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC

677 enrolled

Colorectal Neoplasms

NCT04607668 2024-11-26

PRESERVE1

Phase 3 Terminated

326 enrolled 15 charts

Colorectal Neoplasms

NCT04456699 2024-10-29

LYNK-003

335 enrolled 19 charts

Colorectal Neoplasms

NCT02563002 2024-10-03

KEYNOTE-177

307 enrolled 16 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT04737187 2024-09-24

SUNLIGHT

492 enrolled 22 charts 2 FDA

Colorectal Neoplasms

NCT01607957 2024-09-19

RECOURSE

800 enrolled 12 charts

Colorectal Neoplasms

NCT05223673 2024-08-20

COLSTAR

Phase 3 Terminated

7 enrolled 12 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT03306394 2024-07-25

PRECONNECT

907 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03659448 2024-04-24

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

300 enrolled

Neoplasms, Colorectal Neoplasms

NCT02928224 2023-12-21

BEACON CRC

702 enrolled 82 charts 1 FDA

Colorectal Neoplasms

NCT02753127 2023-11-15

CanStem303C

1,253 enrolled 18 charts