Clinical Trials

Ependymoma, Medulloblastoma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04185038 2026-04-13

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

90 enrolled

Choroid Plexus Carcinoma, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT05278208 2026-04-13

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Phase 1/2 Recruiting

65 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT06161519 2026-03-19

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Phase 1/2 Recruiting

146 enrolled

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Recurrence

NCT04732065 2026-03-17

PNOC023

208 enrolled

Ependymoma, Glioblastoma, Central Nervous System Neoplasms

NCT06193759 2026-03-10

IMPACT

12 enrolled

Ependymoma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT01356290 2026-02-23

MEMMAT

Phase 2 Recruiting

232 enrolled

Ependymoma, Medulloblastoma, Recurrence

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Phase NA Recruiting

20 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT05835687 2026-01-20

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

48 enrolled

Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms, Rhabdoid Tumor

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

37 enrolled

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

102 enrolled

CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT05259605 2025-12-17

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

1,650 enrolled

Ependymoma, Glioma, Hemangiopericytoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Choroid Plexus Neoplasms, Hemangioblastoma

NCT02417324 2025-12-04

International HIT-MED Registry (I-HIT-MED)

500 enrolled

Ependymoma, Medulloblastoma, Pinealoma

NCT03750513 2025-11-13

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

48 enrolled

Ependymoma

NCT06779487 2025-04-11

BIO-RIN

200 enrolled

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma

NCT04648462 2024-11-26

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

1,500 enrolled

Adenoma, Astrocytoma, Craniopharyngioma, Ependymoma, Hemangiopericytoma, Meningioma, Neurilemmoma, Oligodendroglioma, Germinoma, Ganglioglioma, Nerve Sheath Neoplasms, Optic Nerve Glioma

NCT05672043 2023-01-05

GRIPP

400 enrolled