Clinical Trials Browser

Phase 2 × OTHER × Glioblastoma × Clear all

NCT05843253 2026-04-22

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Phase 2 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06069726 2026-04-21

MOAB

Phase 2 Recruiting

Glioblastoma

NCT07462507 2026-04-21

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT06894225 2026-04-20

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Phase 2 Suspended

Glioblastoma

NCT02800486 2026-04-13

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT07521657 2026-04-13

NF118

Phase 2 Not yet recruiting

Glioblastoma, Glioma, Neurofibromatosis 1

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07511725 2026-04-06

PRISM

Phase 2 Recruiting

Glioblastoma

NCT02455557 2026-03-30

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Active not recruiting

66 enrolled 11 charts

Glioblastoma, Gliosarcoma

NCT04559230 2026-03-30

Sacituzumab Govitecan in Recurrent Glioblastoma

Phase 2 Recruiting

Glioblastoma

NCT01743950 2026-03-25

A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Phase 2 Terminated

49 enrolled 19 charts

Glioblastoma, Glioma

NCT03197506 2026-03-25

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Phase 2 Active not recruiting

52 enrolled 19 charts

Glioblastoma, Gliosarcoma

NCT04574856 2026-03-25

Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma

Phase 2 Active not recruiting

Glioblastoma

NCT07476794 2026-03-17

TEMPO

Phase 2 Recruiting

Glioblastoma

NCT05753007 2026-03-16

A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients

Phase 2 Terminated

2 enrolled 13 charts

Glioblastoma

NCT03475186 2026-03-13

Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

Phase 2 Completed

75 enrolled 47 charts

Brain Neoplasms, Glioblastoma, Cognitive Dysfunction

NCT04044937 2026-03-11

UC-GlioFET

Phase 2 Completed

Brain Neoplasms, Glioblastoma

NCT05463848 2026-03-04

Surgical Pembro +/- Olaparib w TMZ for rGBM

Phase 2 Recruiting

Glioblastoma

NCT05607407 2026-03-04

Methimazole in Patients With Progressive Glioblastoma

Phase 2 Recruiting

Glioblastoma, Glioma

NCT07439172 2026-02-27

PRC

Phase 2 Not yet recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT06058988 2026-02-23

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

Phase 2 Recruiting

Brain Neoplasms, Glioblastoma, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT04765514 2026-02-13

Chemoradiotherapy Versus Chemotherapy for Elderly and Frail GBM Patients

Phase 2 Recruiting

Glioblastoma

NCT07263438 2026-02-13

Phenix

Phase 2 Recruiting

Glioblastoma, Recurrence

NCT03405792 2026-02-06

2-THE-TOP

Phase 2 Active not recruiting

40 enrolled 11 charts

Glioblastoma

NCT05653622 2026-02-04

SIB-DOPA

Phase 2 Recruiting

Glioblastoma

NCT05653635 2026-02-04

ReciDOPA

Phase 2 Recruiting

Glioblastoma

NCT05781321 2026-02-03

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

Phase 2 Active not recruiting

Glioblastoma

NCT02394626 2026-02-02

RESURGE

Phase 2 Recruiting

Glioblastoma

NCT05629702 2026-01-30

ARISTOCRAT

Phase 2 Recruiting

Brain Neoplasms, Marijuana Abuse, Glioblastoma, Recurrence

NCT05683808 2026-01-30

VTE-POG

Phase 2 Recruiting

CNSClassical hematology

Astrocytoma, Glioblastoma, Glioma, Venous Thromboembolism

NCT07364786 2026-01-23

AFGBMBiop

Phase 2 Recruiting

Glioblastoma

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Active not recruiting

Glioblastoma

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05465954 2026-01-12

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

Phase 2 Recruiting

Glioblastoma, Gliosarcoma

NCT05871021 2026-01-09

PRIDE

Phase 2 Recruiting

Glioblastoma

NCT04049669 2026-01-08

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Phase 2 Active not recruiting

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma

NCT04221503 2026-01-08

Niraparib/TTFields in GBM

Phase 2 Active not recruiting

Glioblastoma

NCT03743662 2026-01-07

Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated Glioblastoma

Phase 2 Active not recruiting

Glioblastoma

NCT06558214 2026-01-07

OPTIMUS PRIME

Phase 2 Recruiting

Glioblastoma

NCT02617745 2026-01-02

GLIOPLAK

Phase 2 Completed

CNSClassical hematology

Glioblastoma, Thrombocytopenia

NCT04959500 2026-01-02

Newly Diagnosed Glioblastoma

Phase 2 Active not recruiting

Glioblastoma

NCT05879250 2025-12-30

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Recruiting

Glioblastoma

NCT06991101 2025-12-26

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Phase 2 Recruiting

Brain Neoplasms, Glioblastoma

NCT05708352 2025-12-24

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

Phase 2 Recruiting

Glioblastoma

NCT04116411 2025-12-22

VIGAS2

Phase 2 Active not recruiting

Glioblastoma

NCT07285044 2025-12-22

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Phase 2 Recruiting

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT04691960 2025-12-19

A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging

Phase 2 Active not recruiting

Glioblastoma

NCT02177578 2025-12-18

Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

Phase 2 Active not recruiting

Glioblastoma

NCT05183204 2025-12-18

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

Phase 2 Suspended

Glioblastoma

NCT07284628 2025-12-16

ReVoGlio

Phase 2 Not yet recruiting

Glioblastoma