Clinical Trials Browser

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NCT03970447 2026-04-22

GBM AGILE

Phase 2/3 Recruiting

Glioblastoma, Recurrence

NCT05366179 2026-04-22

Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

Phase 1 Recruiting

Brain Neoplasms, Glioblastoma, Recurrence

NCT05843253 2026-04-22

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Phase 2 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT07544992 2026-04-22

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Phase 1 Not yet recruiting

Astrocytoma, Glioblastoma

NCT05917145 2026-04-21

ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma

Phase 1 Recruiting

Glioblastoma

NCT06069726 2026-04-21

MOAB

Phase 2 Recruiting

Glioblastoma

NCT07462507 2026-04-21

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT07541781 2026-04-21

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

Phase 1 Not yet recruiting

Glioblastoma, Glioma

NCT05557292 2026-04-20

RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma

Phase 1 Terminated

Glioblastoma

NCT06894225 2026-04-20

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Phase 2 Suspended

Glioblastoma

NCT07538128 2026-04-20

Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma

Phase EARLY_PHASE1 Recruiting

Adenoviridae Infections, Glioblastoma

NCT02287428 2026-04-17

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Phase 1 Active not recruiting

Glioblastoma

NCT04656535 2026-04-17

AB154 Combined With AB122 for Recurrent Glioblastoma

Phase EARLY_PHASE1 Active not recruiting

Glioblastoma, Recurrence

NCT05698524 2026-04-17

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

Phase 1 Recruiting

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT06466031 2026-04-17

TYR-GLIO

Phase NA Recruiting

Brain Neoplasms, Glioblastoma

NCT03451799 2026-04-15

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

Phase 1 Completed

Glioblastoma

NCT07532031 2026-04-15

APT-HGG

Not yet recruiting

Glioblastoma, Glioma

NCT01507506 2026-04-14

SPECTRO GLIO

Phase 3 Terminated

Glioblastoma

NCT01872221 2026-04-14

STEMRI

Phase NA Completed

Glioblastoma

NCT02866747 2026-04-14

STERIMGLI

Phase 1/2 Completed

Glioblastoma

NCT06512311 2026-04-14

ATTRACT

Phase NA Recruiting

Glioblastoma

NCT06607692 2026-04-14

LUPARPED

Phase 1/2 Recruiting

CNSEndocrineNETSarcoma

Adrenal Cortex Neoplasms, Adrenal Gland Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Paraganglioma, Pheochromocytoma, Recurrence, Osteosarcoma, Sarcoma, Synovial, Esthesioneuroblastoma, Olfactory, Neuroendocrine Tumors

NCT02800486 2026-04-13

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Phase 2 Recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Phase 1 Recruiting

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04528680 2026-04-13

SC9/ABX

Phase 1/2 Active not recruiting

Glioblastoma, Gliosarcoma

NCT05168423 2026-04-13

CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM

Phase 1 Active not recruiting

Glioblastoma

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Phase 1/2 Not yet recruiting

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT07521657 2026-04-13

NF118

Phase 2 Not yet recruiting

Glioblastoma, Glioma, Neurofibromatosis 1

NCT03277638 2026-04-09

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

Phase 1/2 Active not recruiting

Brain Neoplasms, Glioblastoma

NCT04730869 2026-04-09

Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma

Phase NA Completed

Fasting, Glioblastoma, Neoplasms

NCT07134842 2026-04-09

WinGlio-ipi

Phase 1 Recruiting

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT06129760 2026-04-08

Glioblastoma Remote Monitoring and Care - Research Protocol

Phase NA Suspended

CNSClassical hematology

Glioblastoma, Seizures, Venous Thromboembolism

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07512154 2026-04-07

Precision Radiotherapy Enabled by Molecular MRI

Phase NA Not yet recruiting

Brain Neoplasms, Glioblastoma

NCT07515924 2026-04-07

Oral Gallium Maltolate for Recurrent Glioblastoma

Phase EARLY_PHASE1 Not yet recruiting

Glioblastoma

NCT07409584 2026-04-06

SHINE-GLIO

Depression, Glioblastoma, Suicidal Ideation

NCT07488754 2026-04-06

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4)

Phase NA Recruiting

Glioblastoma, Glioma

NCT07511725 2026-04-06

PRISM

Phase 2 Recruiting

Glioblastoma

NCT05095376 2026-04-03

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Phase 3 Active not recruiting

Glioblastoma, Gliosarcoma

NCT05789394 2026-04-02

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy

Phase 1 Recruiting

Astrocytoma, Glioblastoma

NCT06850766 2026-04-02

TMZ-CHRONO

Phase NA Recruiting

Glioblastoma, Neoplasms

NCT06388733 2026-04-01

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma

NCT05839379 2026-03-31

Targeted Pediatric High-Grade Glioma Therapy

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT02455557 2026-03-30

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Active not recruiting

66 enrolled 11 charts

Glioblastoma, Gliosarcoma

NCT03194971 2026-03-30

NovoTTF Treatment Signatures in Glioblastoma Patients at Autopsy

Brain Neoplasms, Glioblastoma

NCT03596086 2026-03-30

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Phase 1/2 Recruiting

Astrocytoma, Glioblastoma

NCT03603405 2026-03-30

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

Phase 1/2 Recruiting

Astrocytoma, Glioblastoma

NCT03663725 2026-03-30

StrateGlio

Phase 3 Active not recruiting

Glioblastoma

NCT04197934 2026-03-30

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Phase 1 Active not recruiting

Astrocytoma, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Lung Neoplasms

NCT04559230 2026-03-30

Sacituzumab Govitecan in Recurrent Glioblastoma

Phase 2 Recruiting

Glioblastoma