Clinical Trials Browser

Glioma

NCT02359565 2026-04-13

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Familial ependymoma, Turcot syndrome, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ependymoma, Glioma, Medulloblastoma

NCT03739411 2026-03-27

Hyperpolarized Imaging in Diagnosing Participants With Glioma

Phase 1 Recruiting

140 enrolled

CNS

Glioma

NCT06650163 2026-02-05

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

Phase 1 Recruiting

20 enrolled

CNS

Brain Neoplasms, Glioma, Meningioma

NCT06964737 2025-10-29

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Phase 1 Recruiting

30 enrolled

CNS

Glioma

NCT02208362 2025-09-03

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Phase 1 Active not recruiting

65 enrolled 21 charts

CNS

Glioblastoma, Glioma

NCT06942104 2025-07-18

Imaging of Solid Tumors Using 18F-TRX

Phase 1 Recruiting

56 enrolled

CNSGenitourinary

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Glioma, Neoplasm Metastasis, Prostatic Neoplasms

NCT06428045 2025-06-22

STARLITE

Phase 1 Recruiting

24 enrolled

CNS

Glioma

NCT03598244 2025-04-20

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Phase 1 Active not recruiting

41 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Glioma, Medulloblastoma, Central Nervous System Neoplasms

NCT04540107 2025-01-10

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Phase 1 Recruiting

300 enrolled

CNS

Glioma

NCT01082926 2015-06-08

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Phase 1 Completed

6 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00110032 2013-01-16

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Phase 1 Terminated

46 enrolled

CNSSarcoma

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

Clinical Trials

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Hyperpolarized Imaging in Diagnosing Participants With Glioma

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Imaging of Solid Tumors Using 18F-TRX

STARLITE

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors