NCT03154996 2026-04-22
Chronic Convection Enhanced Delivery of Topotecan
Columbia University
Phase 1 Completed
Clinical Trials
11 trialsNCT06666712 2026-04-15
TPT CED rHGG
Columbia University
Phase 1 Recruiting
NCT05429502 2025-10-10
Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors
Novartis
Phase 1 Terminated
NCT03927274 2023-05-25
Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma
H. Lee Moffitt Cancer Center and Research Institute
Phase EARLY_PHASE1 Terminated
NCT01004874 2022-04-13
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
Duke University
Phase 2 Completed
NCT00003372 2020-04-08
Topotecan in Treating Patients With Recurrent Brain Tumors
Canadian Cancer Trials Group
Phase 2 Completed
NCT02500459 2019-03-01
Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Terminated
NCT03193463 2019-03-01
Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Withdrawn
NCT02278510 2017-03-31
Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Completed
NCT00610571 2013-10-25
Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas
Duke University
Phase 1 Completed
NCT00541138 2011-09-21
Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors
City of Hope Medical Center
Phase 2 Completed