Clinical Trials

Phase 2 Active not recruiting

Neoplasm Metastasis

NCT05564377 2026-04-21

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Phase 2 Recruiting

2,900 enrolled

Gynecologic

Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT07094204 2026-04-15

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Phase 1 Recruiting

364 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06268015 2026-02-05

BBOpCo

16 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT07021898 2025-12-03

BOREALIS-1

Phase 1 Recruiting

200 enrolled

Neoplasm Metastasis, Neoplasms

NCT06983743 2025-09-11

AURORAS-1

Phase 1 Recruiting

200 enrolled

Neoplasm Metastasis, Neoplasms

NCT02885753 2025-07-09

OSCAR

Phase 3 Recruiting

348 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00819780 2022-12-06

PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors

285 enrolled 31 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00089635 2022-11-07

Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer

203 enrolled 14 charts

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT00113763 2022-11-07

Evaluating Panitumumab (ABX-EGF) Plus Best Supportive Care Versus Best Supportive Care in Patients With Metastatic Colorectal Cancer

Phase 3 Completed

463 enrolled 17 charts

Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00446446 2022-10-05

PRISM (Panitumumab Regimen In Second-line Monotherapy of Head and Neck Cancer)

52 enrolled 17 charts

Head & Neck

Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01001377 2022-09-21

ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Phase 3 Completed

1,010 enrolled 22 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT03142516 2021-06-21

OPALO

20 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT02015923 2021-03-16

CCRe-IV

Phase 4 Terminated

107 enrolled

Colonic Neoplasms, Neoplasm Metastasis

NCT01202409 2020-02-21

CAPOX in KRAS Wild-Type Advanced Adenocarcinoma of the Small Bowel or Ampulla of Vater

19 enrolled 10 charts

Gastrointestinal Neoplasms, Neoplasm Metastasis

NCT02142036 2019-03-13

MetAction

50 enrolled

Neoplasm Metastasis

NCT00418938 2018-10-17

SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial

266 enrolled 17 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00454779 2018-10-17

PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response

113 enrolled 18 charts

Neoplasm Metastasis, Recurrence

NCT01308840 2016-08-17

UGIH09067

31 enrolled 10 charts

Biliary Tract Neoplasms, Gallbladder Neoplasms, Neoplasm Metastasis

NCT00563316 2016-04-12

Effect of Panitumumab on the Pharmacokinetics of Irinotecan

Phase 1 Completed

28 enrolled 11 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00411450 2016-02-15

PRECEPT

116 enrolled 20 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00083616 2014-01-10

Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy

185 enrolled 15 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT00111774 2013-05-14

Evaluating ABX-EGF in Patients With Metastatic ColorectalCarcinoma

150 enrolled

Carcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00950820 2013-03-04

VOXEL

Phase 2 Terminated

9 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00113776 2011-01-21

Evaluating ABX-EGF Extended Therapy in Subjects With MetastaticColorectal Cancer

Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00101920 2010-10-15

ABX-EGF as Second Line Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC)

50 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00346099 2008-01-07

Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum

Phase 2 Withdrawn

Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00034346 2007-12-24

ABX-EGF in Combination With Paclitaxel and Carboplatin for the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC)