Clinical Trials

36 enrolled

Phase 1 Active not recruiting

Pancreatic Neoplasms

NCT06607185 2026-04-22

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT03485209 2026-04-20

innovaTV 207

Phase 2 Active not recruiting

350 enrolled

GastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03403049 2026-04-13

Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer

14 enrolled

Phase 2 Active not recruiting

Neoplasms, Pancreatic Neoplasms

NCT05945823 2026-04-09

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

53 enrolled

Phase 2/3 Active not recruiting

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Pancreatic Neoplasms

NCT06115499 2026-01-07

The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer

10 enrolled

Pancreatic Neoplasms

NCT04858009 2025-12-16

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

40 enrolled

Pancreatic Neoplasms

NCT06783140 2025-12-05

PLATINUM-CAN

Phase 2/3 Recruiting

10 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT04753879 2025-12-04

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

38 enrolled

Pancreatic Neoplasms

NCT04054362 2025-11-21

PINBALL

27 enrolled

Phase 1 Active not recruiting

Pancreatic Neoplasms

NCT02495896 2025-11-10

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

61 enrolled

GastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Gallbladder Neoplasms, Pancreatic Neoplasms

NCT04956640 2025-09-25

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Phase 1/2 Recruiting

540 enrolled

GastrointestinalGynecologicThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05451043 2025-06-26

Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

62 enrolled

Phase 2 Active not recruiting

Biliary Tract Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma

NCT01585805 2025-03-11

Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

88 enrolled

Pancreatic Neoplasms

NCT03535727 2024-12-31

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

48 enrolled 24 charts

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms, Glandular and Epithelial, Pancreatic Diseases, Pancreatic Neoplasms

NCT02009449 2024-11-15

IVY

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

353 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05182112 2024-11-12

Radiation Therapy (RT) and Chemotherapy for the Treatment of Pancreatic Cancer with Homologous Recombination Deficiency That Has Spread to the Liver

1 enrolled

Phase 1 Active not recruiting

Pancreatic Neoplasms

NCT04000906 2024-05-24

Nab-PIPAC

18 enrolled

GastrointestinalGynecologic

Carcinoma, Ovarian Epithelial, Pancreatic Neoplasms, Peritoneal Neoplasms

NCT01825603 2023-12-28

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

17 enrolled

Gallbladder Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT03415854 2023-12-15

NABPLAGEMD

11 enrolled

Adenocarcinoma, Pancreatic Neoplasms

NCT03649321 2023-11-09

Clinical Trial of Chemotherapy and Bemcentinib for Metastatic Pancreatic Cancer

Phase 1/2 Terminated

9 enrolled 12 charts

Pancreatic Neoplasms

NCT02897375 2023-10-10

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

71 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT04953962 2023-08-15

Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancer

36 enrolled

Pancreatic Neoplasms

NCT01726582 2023-08-14

Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")

229 enrolled 14 charts

Adenocarcinoma, Neoplasms, Pancreatic Neoplasms

NCT00049348 2023-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Pancreatic Neoplasms

NCT03410030 2023-04-18

AA NABPLAGEM

27 enrolled

Pancreatic Neoplasms

NCT02227940 2022-07-25

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

38 enrolled

Pancreatic Neoplasms

NCT03102320 2022-06-30

ARCS-Multi

BreastGastrointestinalThoracic

173 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasms, Pancreatic Neoplasms, Thymoma, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT01459614 2021-05-19

Gemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic Cancer

44 enrolled 12 charts

Pancreatic Neoplasms

NCT00112697 2021-02-17

Radiation Therapy and Docetaxel With Either Fluorouracil or Cisplatin as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery

71 enrolled

Pancreatic Neoplasms

NCT03697239 2019-06-11

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT03797443 2019-05-31

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT03908333 2019-05-30

High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT01893801 2019-05-29

Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDA

25 enrolled 17 charts

GastrointestinalGynecologicHead & NeckThoracic

Pancreatic Neoplasms

NCT02433626 2019-02-01

COTI2-101

Phase 1 Unknown

51 enrolled

Squamous Cell Carcinoma of Head and Neck, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03668418 2018-09-12

xenoZ

Unknown

120 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT00262951 2017-12-28

Chemoradiation in Locally Advanced Pancreatic Cancer

Phase 2 Terminated

23 enrolled 8 charts

Pancreatic Neoplasms

NCT00703638 2017-11-29

Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

16 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT01150630 2017-09-01

PACT-15

98 enrolled

Pancreatic Neoplasms

NCT01730222 2017-09-01

PACT-19

137 enrolled

Disease, Pancreatic Neoplasms

NCT00059826 2016-12-07

Adjuvant Chemoradiotherapy and Interferon Alfa in Treating Patients With Resected Pancreatic Cancer

89 enrolled

Pancreatic Neoplasms

NCT01661114 2016-10-19

A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers

39 enrolled 7 charts

Biliary Tract Neoplasms, Pancreatic Neoplasms

NCT01188109 2016-09-28

Gemcitabine/Cisplatin for Resected Pancreas Cancer: Establishing the Role of ERCC1 in Treatment Decision

Phase 2 Terminated

25 enrolled 8 charts

Pancreatic Neoplasms

NCT00003157 2016-07-14

Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas or Stomach

26 enrolled

Pancreatic Neoplasms, Stomach Neoplasms

NCT00012220 2016-07-14

Gemcitabine Alone or in Combination With Other Chemotherapy Drugs in Treating Patients With Metastatic Cancer of the Pancreas

259 enrolled

Pancreatic Neoplasms

NCT00026403 2016-07-14

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Pancreatic Cancer

48 enrolled

Pancreatic Neoplasms

NCT01296763 2016-03-22

Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer

18 enrolled 12 charts

Pancreatic Neoplasms

NCT00002854 2015-08-26

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

33 enrolled

Carcinoma, Ovarian Epithelial, Anus Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Wilms Tumor, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT01167738 2015-04-24

PACT-17

Phase 2 Terminated

60 enrolled

Pancreatic Neoplasms

NCT00785421 2015-01-08

PROSPECT

Phase 2/3 Completed

312 enrolled