NCT07252739 2026-04-17KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)Merck Sharp & Dohme LLCPhase 2 Recruiting130 enrolled
NCT03358472 2025-12-03Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)Incyte CorporationPhase 3 Completed89 enrolled 14 charts
NCT02358031 2025-07-18MK-3475-048Merck Sharp & Dohme LLCPhase 3 Completed882 enrolled 50 charts 1 FDA
NCT02563002 2024-10-03KEYNOTE-177Merck Sharp & Dohme LLCPhase 3 Completed307 enrolled 16 charts 1 FDA
NCT03342352 2019-12-20Nivolumab Plus Epacadostat in Combination With Chemotherapy Versus the EXTREME Regimen in Squamous Cell Carcinoma of the Head and Neck (CheckMate 9NA/ECHO-310)Incyte CorporationPhase 3 Withdrawn