Clinical Trials

Rectal Neoplasms

NCT07528209 2026-04-14

Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer

Phase 3 Recruiting

556 enrolled

Rectal Neoplasms

NCT02688712 2026-04-13

ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer

50 enrolled

Rectal Neoplasms

NCT06417476 2026-04-13

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

66 enrolled

Rectal Neoplasms

NCT06837831 2026-04-13

Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin

274 enrolled

Rectal Neoplasms

NCT07404228 2026-04-13

RESTAGE

Not yet recruiting

115 enrolled

Rectal Neoplasms

NCT07501845 2026-04-13

Registry Maastro Applicator

Recruiting

999 enrolled

Rectal Neoplasms

NCT04624555 2026-04-09

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Recruiting

50 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06746012 2026-04-09

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

70 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06162650 2026-04-08

Total Neoadjuvant Therapy in Rectal Cancer

Phase 2 Recruiting

42 enrolled

Rectal Neoplasms

NCT07283939 2026-04-07

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

420 enrolled

Phase 2 Not yet recruiting

Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07516210 2026-04-07

ART-Hypo

264 enrolled

GastrointestinalGenitourinaryGynecologic

Uterine Cervical Neoplasms, Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT02107105 2026-04-06

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

Recruiting

430 enrolled

Rectal Neoplasms

NCT06048146 2026-04-06

A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node Metastasis

Phase NA Completed

180 enrolled

Gastrointestinal Neoplasms, Intestinal Neoplasms, Lymphatic Metastasis, Rectal Diseases, Rectal Neoplasms

NCT07292298 2026-04-06

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Phase 2 Recruiting

44 enrolled

Rectal Neoplasms

NCT07512232 2026-04-06

TOWER-2

1,598 enrolled

Phase NA Not yet recruiting

Rectal Neoplasms

NCT07499921 2026-04-03

BIOREC

300 enrolled

Phase 2 Not yet recruiting

Rectal Neoplasms

NCT07509424 2026-04-03

Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Locally Advanced HER2-expressing Rectal Cance

29 enrolled

Rectal Neoplasms

NCT07509632 2026-04-03

Predicting Pathological Complete Response in Rectal Cancer Using Machine Learning

Active not recruiting

320 enrolled

Rectal Neoplasms

NCT05080673 2026-04-02

FORTE

9,500 enrolled

Phase EARLY_PHASE1 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms

NCT05108428 2026-04-01

Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma

20 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT05515796 2026-04-01

Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors

Phase 2 Completed

189 enrolled

Rectal Neoplasms, Stomach Neoplasms

NCT07505472 2026-04-01

STARS-RC10

Phase 2/3 Recruiting

212 enrolled

Rectal Neoplasms

NCT02437656 2026-03-31

METCAP

Phase 2 Completed

60 enrolled

Rectal Neoplasms

NCT04963283 2026-03-31

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

48 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04703101 2026-03-30

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Phase 1 Recruiting

25 enrolled

Rectal Neoplasms

NCT04503694 2026-03-27

REGINA

72 enrolled

Rectal Neoplasms

NCT07494201 2026-03-27

MIMICC

2,500 enrolled

Colonic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms, Anastomotic Leak

NCT06698289 2026-03-25

Preoperative Sarcopenia and Surgical Outcomes in Colorectal Cancer Patients

Completed

70 enrolled

Colonic Neoplasms, Rectal Neoplasms, Sarcopenia

NCT07369531 2026-03-25

FIAS

520 enrolled

Neoplasms, Rectal Neoplasms

NCT06006260 2026-03-20

Changes of Low Anterior Resection Syndrome and Balance Ability in Patients With Rectal Cancer.

Completed

107 enrolled