Clinical Trials

Rectal Neoplasms

NCT07528209 2026-04-14

Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer

Phase 3 Recruiting

556 enrolled

Rectal Neoplasms

NCT06837831 2026-04-13

Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin

274 enrolled

Rectal Neoplasms

NCT06746012 2026-04-09

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

70 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06162650 2026-04-08

Total Neoadjuvant Therapy in Rectal Cancer

42 enrolled

Rectal Neoplasms

NCT07283939 2026-04-07

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

420 enrolled

Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07292298 2026-04-06

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

44 enrolled

Rectal Neoplasms

NCT07512232 2026-04-06

TOWER-2

1,598 enrolled

Rectal Neoplasms

NCT05080673 2026-04-02

FORTE

9,500 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT07505472 2026-04-01

STARS-RC10

Phase 2/3 Recruiting

212 enrolled

Rectal Neoplasms

NCT04703101 2026-03-30

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Phase 1 Recruiting

25 enrolled

Rectal Neoplasms

NCT07494201 2026-03-27

MIMICC

2,500 enrolled

Colonic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms, Anastomotic Leak

NCT07369531 2026-03-25

FIAS

520 enrolled

GastrointestinalGynecologic

Neoplasms, Rectal Neoplasms

NCT07213609 2026-03-23

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Phase 1/2 Recruiting

47 enrolled

Turcot syndrome, Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06628674 2026-03-20

Developing and Testing the Effect of Online Interactive Videos in Improving Low Anterior Resection Syndrome.

110 enrolled

Rectal Neoplasms

NCT04674267 2026-03-18

REACH

257 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05806931 2026-03-18

SCOTI

50 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06637462 2026-03-18

A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer

30 enrolled

Rectal Neoplasms

NCT07011576 2026-03-18

FRUITFUL

60 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07351071 2026-03-17

SECURE

137 enrolled

Colonic Diseases, Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases, Postoperative Complications, Rectal Diseases, Rectal Neoplasms, Anastomotic Leak

NCT04808323 2026-03-16

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

Phase 1 Recruiting

22 enrolled

Rectal Neoplasms

NCT07474103 2026-03-16

SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC

49 enrolled

Rectal Neoplasms

NCT06607458 2026-03-13

DEL-LIVER

90 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT07209787 2026-03-13

SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak

Phase 4 Recruiting

966 enrolled

Rectal Neoplasms

NCT06802172 2026-03-10

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

100 enrolled

BreastGastrointestinal

Intermittent Fasting, Breast Neoplasms, Rectal Neoplasms

NCT07458529 2026-03-10

NCRIT-PM9

50 enrolled

Rectal Neoplasms

NCT06647680 2026-03-06

Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01）

35 enrolled

Pathologic Complete Response, Rectal Neoplasms

NCT05731726 2026-03-05

Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer

50 enrolled

Rectal Neoplasms

NCT06952101 2026-03-05

INTERPRETE

200 enrolled

Rectal Neoplasms

NCT05672524 2026-03-04

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

37 enrolled

Adenocarcinoma, Rectal Neoplasms

NCT04215731 2026-03-03

FOBEAR

Phase 3 Recruiting

582 enrolled

Rectal Neoplasms

NCT06769061 2026-02-25

AcuCIN

75 enrolled

Rectal Neoplasms

NCT07433673 2026-02-25

GAP Cemi

20 enrolled

Rectal Neoplasms

NCT07427901 2026-02-23

Quality Of Life In Colorectal Cancer Survivors

368 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes