Clinical Trials

370 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07423078 2026-04-13

WOLF

87 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT06992427 2026-04-07

HOPE

228 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04892173 2026-03-13

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

500 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07026474 2026-03-02

RePaIr-HN

214 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07044635 2026-02-27

RAD RAPTORS

42 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05268614 2026-02-18

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

250 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05962242 2026-02-05

HN001

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04754321 2026-02-02

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

Phase 1 Recruiting

45 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07371611 2026-01-28

Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma

104 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07369882 2026-01-27

Comparison of Efficacy Between De-escalated Surgery and Standard Surgery After Neoadjuvant Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase NA Recruiting

60 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06998069 2025-12-30

Head and Neck Cancer Study Project in the Geriatric Population

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07040956 2025-12-29

A Clinical Trial Comparing Low-Dose RT + Targeted Therapy+ Immunotherapy vs Targeted Therapy+ Immunotherapy Alone as Neoadjuvant Therapy in Operable HNSCC Patients.

98 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07121595 2025-08-13

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

50 enrolled

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT07055841 2025-07-09

Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

69 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06494995 2025-06-04

AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy

52 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Squamous Cell Carcinoma of Head and Neck

NCT06673693 2025-04-16

NEOSTART

24 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05784012 2025-03-13

RADIAN

Phase 1/2 Recruiting

34 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06725498 2024-12-10

Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC

50 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05872880 2023-05-24

TPExtreme Induced Chemotherapy Followed by Surgery and Radiotherapy in the Oral Carcinoma.

Recruiting

124 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05343325 2022-12-29

The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC

25 enrolled