Clinical Trials Browser

Breast Neoplasms

Posterior Fossa Ependymal Tumor

Erythroplasia, Leukoplakia, Oral

Urothelial Cancer

Erythroplasia, Hyperplasia, Leukoplakia, Oral, Mouth Neoplasms

Rectal Neoplasms

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant

Prostatic Neoplasms

Smoldering Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance

Leukoplakia, Oral

Endometrial Hyperplasia, Endometrial Neoplasms

Carcinoma, Intraductal, Noninfiltrating

Squamous Cell Carcinoma of Head and Neck

Glioblastoma

Glioblastoma

Thyroid Diseases

Glioblastoma

Endometrial Neoplasms

Prediabetic State

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung

Lung Neoplasms

Polycystic Ovary Syndrome

Leukemia, Lymphocytic, Chronic, B-Cell

Brain Neoplasms

Breast Neoplasms, Hyperglycemia, Neoplasm Metastasis, Multiple Endocrine Neoplasia Type 1

Glioblastoma, Glioma, Neoplasms

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

Glioblastoma

Ovarian Neoplasms, Endometrial Neoplasms

Clinical Trials

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

PNOC041

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

METCAP

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Metformin and Nightly Fasting in Women With Early Breast Cancer

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers

OPTIMUM

A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome

A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

METALLICA

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

MEMENTO

Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer