Clinical Trials

21 enrolled

CNS

Brain Neoplasms, Meningeal Carcinomatosis

NCT04521686 2026-04-22

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

200 enrolled

Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Glioblastoma, Glioma, Melanoma, Prostatic Neoplasms, Thyroid Neoplasms, Central Nervous System Neoplasms, Cholangiocarcinoma

NCT04692831 2026-04-22

Testing a New Imaging Agent to Identify Cancer

60 enrolled

HER-2 Positive Malignant Carcinoma of Breast

NCT05627245 2026-04-22

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

48 enrolled

DermatologicLymphoid

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT05757700 2026-04-22

Study of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Lymphoma

30 enrolled

Lymphoid

Lymphoma, B-Cell

NCT06555744 2026-04-22

A Study of ZW191 in Participants With Solid Tumors

145 enrolled

Tumor-Agnostic

Neoplasms

NCT06607185 2026-04-22

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06898957 2026-04-22

(DeLLphi-310)

200 enrolled

Thoracic

Small Cell Lung Carcinoma

NCT01590069 2026-04-21

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

DermatologicGenitourinarySarcoma

70 enrolled

Carcinoma, Renal Cell, Melanoma, Sarcoma, Osteosarcoma

NCT02204098 2026-04-21

Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy

27 enrolled

Breast Neoplasms

NCT02862275 2026-04-21

Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer

Other hematologic neoplasm

40 enrolled

Neoplasm Metastasis, Hematologic Neoplasms

NCT04106219 2026-04-21

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

71 enrolled

CNS

Epilepsy, Neuroblastoma

NCT05537740 2026-04-21

A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors

BreastDermatologicHead & NeckThoracic

129 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Recurrence, Triple Negative Breast Neoplasms

NCT01281176 2026-04-20

High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid Tumors

20 enrolled

Adult Solid Neoplasm

NCT02717624 2026-04-20

A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL

72 enrolled

Lymphoid

Lymphoma, Mantle-Cell

NCT03328273 2026-04-20

A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

LymphoidOther hematologic neoplasm

12 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell

NCT03655002 2026-04-20

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

8 enrolled

Carcinoma, Hepatocellular

NCT04605731 2026-04-20

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

25 enrolled

Carcinoma, Hepatocellular

NCT04883957 2026-04-20

Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies

64 enrolled

Lymphoid

Mature B-cell Malignancies

NCT05020678 2026-04-20

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

LymphoidOther hematologic neoplasmSarcoma

150 enrolled

Burkitt Lymphoma, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Mantle-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT05068102 2026-04-20

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

DermatologicHead & NeckThoracic

14 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05222984 2026-04-20

Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax

Other hematologic neoplasm

17 enrolled

Leukemia, Myeloid, Acute

NCT05307705 2026-04-20

PIKASSO-01

193 enrolled

Breast Neoplasms

NCT05571839 2026-04-20

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

DermatologicGastrointestinalOther solid neoplasmThoracic

41 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05813327 2026-04-20

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

6 enrolled

Sarcoma

Sarcoma, Ichthyosis, X-Linked

NCT01746238 2026-04-17

Bevacizumab/Doxorubicin/Radiation for Sarcoma

14 enrolled

Sarcoma

NCT02287428 2026-04-17

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

56 enrolled

CNS

Glioblastoma

NCT04092270 2026-04-17

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

54 enrolled

Gynecologic

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms

NCT04750954 2026-04-17

Testing the Addition of An Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Pancreatic Neuroendocrine Tumors

29 enrolled

EndocrineNET

Neuroendocrine Tumors

NCT05081492 2026-04-17

CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer

9 enrolled

Triple Negative Breast Neoplasms

NCT05359445 2026-04-17

IMA401 TCER® in Recurrent and/or Refractory Solid Tumors, Alone or in Combination With a Checkpoint Inhibitor

95 enrolled

Neoplasms, Recurrence

NCT06052306 2026-04-17

A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

232 enrolled

Genitourinary

Metastatic Castration-resistant Prostate Cancer

NCT06544655 2026-04-17

A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

GastrointestinalHead & NeckThoracic

213 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Spinocerebellar Degenerations, Colorectal Neoplasms

NCT06545942 2026-04-17

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

BreastGastrointestinalGenitourinaryGynecologic

220 enrolled

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT00479128 2026-04-16

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

80 enrolled

Genitourinary

Urinary Bladder Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT01187199 2026-04-16

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

278 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT02626312 2026-04-16

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

36 enrolled

Fibrosis, Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT03133650 2026-04-16

A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing

12 enrolled

Esophagogastric Cancer

NCT03435952 2026-04-16

Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT

18 enrolled

BreastGenitourinary

Breast Neoplasms, Urologic Neoplasms

NCT03853616 2026-04-16

MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)

LymphoidOther hematologic neoplasm

48 enrolled

Acute Lymphoblastic Leukemia Recurrent

NCT05470283 2026-04-16

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

21 enrolled

Dermatologic

Melanoma, Neoplasms

NCT05497778 2026-04-16

A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.

19 enrolled

Pancreatic Neoplasms

NCT06049212 2026-04-16

TroFuse-008

30 enrolled

Thoracic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT06082960 2026-04-16

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

45 enrolled

Other solid neoplasm

Solid Tumors

NCT01955460 2026-04-15

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

34 enrolled

Dermatologic

Melanoma

NCT03132454 2026-04-15

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

LymphoidOther hematologic neoplasm

32 enrolled

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03162627 2026-04-15

Selumetinib and Olaparib in Solid Tumors

90 enrolled

Breast Neoplasms

NCT03168737 2026-04-15

18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients

25 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms, Pancreatic Neoplasms

NCT03634267 2026-04-15

MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer