Clinical Trials

25 enrolled

Advanced Solid Tumor

NCT05198349 2026-04-22

First in Human Study of M1069 in Advanced Solid Tumors

15 enrolled 18 charts

Neoplasm Metastasis

NCT05365581 2026-04-22

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

398 enrolled

Adenocarcinoma

NCT05683418 2026-04-22

A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

241 enrolled

Breast

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT06257264 2026-04-22

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

BreastGastrointestinalGenitourinaryGynecologicThoracic

258 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06555744 2026-04-22

A Study of ZW191 in Participants With Solid Tumors

145 enrolled

Neoplasms

NCT06607185 2026-04-22

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06625593 2026-04-22

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

168 enrolled

Advanced Solid Tumor

NCT06779851 2026-04-22

SUMMIT-1

20 enrolled

Advanced Solid Tumors

NCT06840886 2026-04-22

A Study of PHST001 in Advanced Solid Tumors

CNSGastrointestinalGynecologic

272 enrolled

Ovarian Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06898957 2026-04-22

(DeLLphi-310)

200 enrolled

Thoracic

Small Cell Lung Carcinoma

NCT07085091 2026-04-22

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

GastrointestinalHead & NeckThoracic

170 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT07211659 2026-04-22

OCTOPOD-IP

18 enrolled

Gynecologic

Ovarian Neoplasms

NCT07222267 2026-04-22

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

86 enrolled

Breast

Breast Neoplasms

NCT07387068 2026-04-22

Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors

121 enrolled

Advanced Solid Tumors

NCT07543744 2026-04-22

A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibix® in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI

180 enrolled

Colorectal Neoplasms

NCT07544589 2026-04-22

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

66 enrolled

Adenocarcinoma Of Esophagus, Adenoviridae Infections, Gastrointestinal Neoplasms, Colorectal Neoplasms

NCT07545122 2026-04-22

CT-202

162 enrolled

BreastGastrointestinal

Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT07545356 2026-04-22

A Study of KIVU-305 in Participants With Locally Advanced or Metastatic Solid Tumors

76 enrolled

Colorectal Neoplasms

NCT07545811 2026-04-22

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

43 enrolled

Prostatic Neoplasms

NCT04106219 2026-04-21

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

71 enrolled

CNS

Epilepsy, Neuroblastoma

NCT05276310 2026-04-21

A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy

62 enrolled

Advanced Cancer

NCT05376527 2026-04-21

Open Multi-cohort Study of the First Phase of Safety of a Drug Based on Double Recombinant Vaccinia Virus VV-GMCSF-Lact

Phase 1 Completed

34 enrolled 18 charts

Breast

Breast Neoplasms, Vaccinia

NCT05537740 2026-04-21

A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors

BreastDermatologicHead & NeckThoracic

129 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Recurrence, Triple Negative Breast Neoplasms

NCT06163898 2026-04-21

A Study to Evaluate Alnuctamab in Combination With Mezigdomide in Participants With Relapsed and/or Refractory Multiple Myeloma

4 enrolled

Plasma cell

Multiple Myeloma

NCT06480552 2026-04-21

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

240 enrolled

Advanced Solid Tumors

NCT06532565 2026-04-21

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

154 enrolled

Advanced Solid Tumors

NCT06586957 2026-04-21

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicThoracic

150 enrolled

Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Uterine Diseases, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06884618 2026-04-21

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

405 enrolled

Neoplasms

NCT06966024 2026-04-21

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

60 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell

NCT06997029 2026-04-21

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

234 enrolled

Neoplasms

NCT07020117 2026-04-21

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

BreastHead & NeckThoracic

150 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Triple Negative Breast Neoplasms

NCT07204340 2026-04-21

TLN-372 in Advanced KRAS Mutant Solid Tumors

240 enrolled

KRAS Mutant Solid Tumors

NCT07206225 2026-04-21

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

294 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT07260708 2026-04-21

Clinical Trial of TQB2922 Injection (Subcutaneous Injection) in Patients With Advanced Cancers

42 enrolled

Advanced Cancers

NCT07261631 2026-04-21

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

BreastGastrointestinalSarcomaThoracic

180 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Sarcoma, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT07304154 2026-04-21

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

52 enrolled

Multiple Sclerosis, Myasthenia Gravis, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

NCT07346846 2026-04-21

A Study of BGM-2121 in Patients With Advanced Solid Tumors

35 enrolled

Advanced Solid Tumors

NCT07360314 2026-04-21

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & Neck

138 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Ovarian Neoplasms, Stomach Neoplasms

NCT07524322 2026-04-21

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

63 enrolled

BreastGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT07535112 2026-04-21

A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

130 enrolled

Advanced/Metastatic Colorectal Adenocarcinoma

NCT07541534 2026-04-21

A Phase I Clinical Study of HLX316 in Participants With Advanced/Metastatic Solid Tumors

41 enrolled

Advanced/Metastatic Solid Tumors

NCT07542704 2026-04-21

A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies

GastrointestinalGynecologicThoracic

48 enrolled

Carcinoma, Non-Small-Cell Lung, Uterine Neoplasms, Colorectal Neoplasms

NCT07543055 2026-04-21

A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread

36 enrolled

Neoplasm Metastasis, Prostatic Neoplasms, Recurrence

NCT07543471 2026-04-21

PK equivalence

387 enrolled

mCRC

NCT02298153 2026-04-20

A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma

29 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02717624 2026-04-20

A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL

72 enrolled

Lymphoid

Lymphoma, Mantle-Cell

NCT03328273 2026-04-20

A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

LymphoidOther hematologic neoplasm

12 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell

NCT04389632 2026-04-20

A Study of Sigvotatug Vedotin in Advanced Solid Tumors