Clinical Trials Browser

Terminated × Has results × Metformin × Clear all

NCT02874430 2026-04-22

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Phase 2 Terminated

29 enrolled 11 charts

Breast Neoplasms

NCT02946996 2026-03-05

Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Phase 2 Terminated

41 enrolled 8 charts

Prostatic Neoplasms

NCT03109847 2025-12-11

Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers

Phase 2 Terminated

13 enrolled 8 charts

Thyroid Diseases

NCT02500147 2025-07-02

Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)

Phase 4 Terminated

3 enrolled 5 charts

Acne Vulgaris, Amenorrhea, Hirsutism, Polycystic Ovary Syndrome, Metabolic Syndrome, Dyslipidemias, Non-alcoholic Fatty Liver Disease

NCT00984490 2024-02-01

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Phase NA Terminated

5 enrolled 4 charts

Breast Neoplasms

NCT03477162 2023-10-03

Metformin Pharmacology in Human Cancers: A Proof of Principle Study

Phase EARLY_PHASE1 Terminated

18 enrolled 10 charts

Thoracic Neoplasms

NCT02420652 2023-02-08

PRIMA

Phase 2 Terminated

27 enrolled 6 charts

Prostatic Neoplasms

NCT02531308 2022-09-28

DLBCL

Phase 2 Terminated

5 enrolled 5 charts

LymphoidSarcoma

Lymphoma, Lymphoma, Large B-Cell, Diffuse, Dendritic Cell Sarcoma, Interdigitating

NCT01482286 2022-03-15

PULSE

Phase 3 Terminated

32 enrolled 10 charts

Body Weight, Insulin Resistance, Motor Activity, Polycystic Ovary Syndrome

NCT02495103 2021-01-26

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Phase 1/2 Terminated

7 enrolled 10 charts

Carcinoma, Renal Cell

NCT01627067 2020-06-19

Exemestane-RAD001-Metformin

Phase 2 Terminated

23 enrolled 7 charts

Breast Neoplasms

NCT01717482 2020-03-10

Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

Phase 2 Terminated

6 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02285855 2020-01-06

Metformin in Non Small Cell Lung Cancer (NSCLC)

Phase 2 Terminated

27 enrolled 11 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02472353 2019-10-16

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Phase 2 Terminated

30 enrolled 10 charts

Breast Neoplasms, Neoplasms, Cardiotoxicity

NCT01849276 2019-01-31

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

Phase 1 Terminated

2 enrolled 9 charts

Other hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT01578551 2018-12-19

Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

Phase 2 Terminated

25 enrolled 9 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

NCT02019979 2018-05-04

METRO

Phase 2 Terminated

14 enrolled 7 charts

Lung Neoplasms

NCT02815397 2017-11-17

DLBCL

Phase 2 Terminated

2 enrolled 3 charts

Lymphoma, Large B-Cell, Diffuse

NCT02360059 2017-08-17

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

Phase 2 Terminated

1 enrolled 3 charts

Breast Neoplasms

NCT01215032 2017-05-15

Metformin in Castration-Resistant Prostate Cancer

Phase 2 Terminated

21 enrolled 8 charts

Prostatic Neoplasms

NCT01632020 2016-07-11

Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth

Phase 2 Terminated

7 enrolled 6 charts

Gastrointestinal

Colorectal Neoplasms

NCT01486043 2015-01-30

Metformin and Transient Hyperglycemia

Phase NA Terminated

4 enrolled 9 charts

LymphoidOther hematologic neoplasm

Diabetes Mellitus, Hyperglycemia, Insulin Resistance, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00682890 2014-08-20

Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)

Phase 4 Terminated

28 enrolled 7 charts

Insulin Resistance, Polycystic Ovary Syndrome