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NCT04641078 2024-02-28

DART

Phase 2 Unknown

124 enrolled

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT04176081 2024-01-24

SChLAP/IDC

Phase 2 Not yet recruiting

208 enrolled

BreastGenitourinary

Carcinoma, Intraductal, Noninfiltrating, Prostatic Neoplasms

NCT06177015 2023-12-26

Intermittent Darolutamide Treatment in the Triple Therapy of mHSPC

Phase 3 Recruiting

200 enrolled

Genitourinary

Prostatic Neoplasms

NCT04737109 2023-11-13

ADDItion

Phase 1/2 Terminated

6 enrolled 9 charts

Genitourinary

Prostatic Neoplasms

NCT05771896 2023-09-14

CARE

Phase 3 Withdrawn

Genitourinary

Prostatic Neoplasms

NCT05900973 2023-08-07

A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer

Phase 2 Unknown

19 enrolled

Genitourinary

Prostatic Neoplasms

Clinical Trials

DIVINE

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial

Darolutamide in Patients With Androgen Receptor-Positive Salivary Gland Carcinoma (DISCOVARY)

Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

THUNDER

Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer

PSMA PET/CT-Based Multimodal Model for Predicting Response to First-Line Therapy in mHSPC.

ANDARP

Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response

Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)

Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer

SOGUG-PRINCIS

Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression

ExBAT

COAction

Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer

Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.

INTREPId (INTermediate Risk Erection PreservatIon Trial)

Darolutamide+ADT Post-RP w/o ePLND in hrPC: Briganti 2019

ARACOG

Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC

Study on Triple Therapy Combined With HIFU for High-Tumor-Burden mHSPC

DECREASE

PEACE 7

PICASSO

ODENZA

ProBio

PSA-DEEP02

Physical Function During ARSI Treatment

PEACE8

Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)

Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)

ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable)

Neoadjuvant Therapy of Darolutamide Plus ADT for High Risk Prostate Cancer

DAROTAXEL

ECHOS

Efficacy and Safety of Darolutamide in Combination With Androgen-Deprivation Therapy in Prostate Cancer Patients With Lymph Node-positive After Radical Prostatectomy: A Prospective Observational Cohort Study

OLIGOMET

CURATE

ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents.

ALADDIN

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

DART

SChLAP/IDC

Intermittent Darolutamide Treatment in the Triple Therapy of mHSPC

ADDItion

CARE

A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer