NCT06346067 2026-02-27A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)Erasca, Inc.Phase 3 Active not recruiting78 enrolled
NCT04940052 2025-12-02Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid CancerNovartisPhase 3 Active not recruiting153 enrolled
NCT01584648 2021-02-17A Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant MelanomaNovartisPhase 3 Completed423 enrolled 15 charts
NCT01245062 2018-04-05GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive MelanomaGlaxoSmithKlinePhase 3 Completed322 enrolled 24 charts