Clinical Trials

246 enrolled

Plasma cell

Multiple Myeloma

NCT05006716 2026-04-22

CaDAnCe-101

614 enrolled

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT05455619 2026-04-22

Amelia-1

52 enrolled

Breast

Breast Neoplasms, Hyperglycemia, Hyperinsulinism, Insulin Resistance

NCT05975073 2026-04-22

A Phase 1/2 Study of Anvumetostat in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors

53 enrolled

Tumor-Agnostic

Neoplasms

NCT06614140 2026-04-22

Personalized Neoantigen Cancer Vaccine for Patients With Solid Tumors

8 enrolled

Tumor-Agnostic

Neoplasms

NCT06785636 2026-04-22

P300

252 enrolled

Genital Neoplasms, Male, Neoplasms, Neoplasms by Site, Prostatic Diseases, Prostatic Neoplasms, Urogenital Neoplasms, Male Urogenital Diseases

NCT06898450 2026-04-22

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

134 enrolled

Werner Syndrome, Microsatellite Instability

NCT06922591 2026-04-22

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

183 enrolled

Lung Neoplasms

NCT07020221 2026-04-22

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

295 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07136779 2026-04-22

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

310 enrolled

Participants With Advanced Solid Tumor Malignancies

NCT07299747 2026-04-22

Clinical Trial of VBC103 in Patients With Advanced Malignant Solid Tumors

255 enrolled

Participants With Advanced Solid Tumor Malignancies

NCT07332455 2026-04-22

First-Time-in-Human Study of GSK5471713 in Adults With mCRPC

54 enrolled

Prostatic Neoplasms

NCT07545265 2026-04-22

SKB565 for Injection in Advanced Solid Tumors

180 enrolled

Advanced Solid Tumors

NCT01604889 2026-04-21

A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma

Phase 1/2 Terminated

50 enrolled

Dermatologic

Melanoma, Neoplasms, Skin Neoplasms

NCT03837899 2026-04-21

Durvalumab and Tremelimumab for Pediatric Malignancies

Other hematologic neoplasm

50 enrolled 59 charts

Neoplasms, Hematologic Neoplasms

NCT04067336 2026-04-21

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

263 enrolled 2 FDA

Leukemia, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05615623 2026-04-21

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

10 enrolled

CNS

Brain Neoplasms

NCT05732831 2026-04-21

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

GastrointestinalOther solid neoplasmSarcomaThoracic

225 enrolled

Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT05786924 2026-04-21

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

CNSGastrointestinalHead & NeckMyeloidThoracic

554 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Histiocytosis

NCT06137144 2026-04-21

PRIMAVERA

161 enrolled

Lymphoid

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, T-Cell, Peripheral

NCT06966453 2026-04-21

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

100 enrolled

Breast

Breast Neoplasms

NCT06975293 2026-04-21

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

107 enrolled

Sarcoma

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT07100106 2026-04-21

MoonROSE

285 enrolled

Breast

Breast Neoplasms

NCT07407283 2026-04-21

A Clinical Study of SHR-4394 in Combination With Anti-tumor Therapy in Prostate Cancer

100 enrolled

Prostatic Neoplasms

NCT01802632 2026-04-20

AURA

603 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT02174549 2026-04-20

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

EndocrineGastrointestinalNET

25 enrolled

Hypoxia, Carcinoma, Hepatocellular, Neuroendocrine Tumors

NCT02734004 2026-04-20

MEDIOLA

BreastGastrointestinalGynecologicThoracic

264 enrolled 32 charts

Breast Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT03761108 2026-04-20

LINKER-MM1

387 enrolled 2 FDA

Plasma cell

Multiple Myeloma, Recurrence

NCT03833206 2026-04-20

A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients

12 enrolled

Depressive Disorder, Major

NCT03932331 2026-04-20

Study of Acalabrutinib in Chinese Adult Subjects With Relapsed or Refractory Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia or Other B-cell Malignancies

105 enrolled 34 charts

Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Mantle-Cell

NCT05189093 2026-04-20

Recombinant Humanized Anti-CD47/PD-1 Bifunctional Antibody HX009 in Patients With Relapsed/Refractory Lymphoma

48 enrolled

Lymphoid

Lymphoma

NCT05482568 2026-04-20

A Trial of Injectable SHR-A1811 in Combination With Pyrotinib or SHR-1316 in Subjects With Advanced Non-small Cell Lung Cancer

324 enrolled

Advanced Non-small Cell Lung Cancer

NCT05764928 2026-04-20

Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Pemetrexed + Cisplatin Therapy

32 enrolled

Nonsquamous Nonsmall Cell Neoplasm of Lung

NCT05789082 2026-04-20

KRAScendo 170

320 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05875168 2026-04-20

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

540 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT06780137 2026-04-20

MK-6070-002

262 enrolled

Small Cell Lung Carcinoma

NCT06863272 2026-04-20

IDeate-Prostate02

360 enrolled

Neoplasm Metastasis, Prostatic Neoplasms, Castration-Resistant

NCT07227012 2026-04-20

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

138 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07227298 2026-04-20

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

162 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07227415 2026-04-20

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

224 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT07421700 2026-04-20

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

132 enrolled

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT07446855 2026-04-20

PARTHENON

180 enrolled

Solid Tumours

NCT07538804 2026-04-20

A Study to Investigate ANS02 in Participants With EGFR Mutation-Positive Non-Small Cell Lung Cancer

294 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07540572 2026-04-20

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

160 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Spinocerebellar Degenerations, Colorectal Neoplasms

NCT03960840 2026-04-17

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

217 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04174716 2026-04-17

VASTUS

108 enrolled

Solid Tumors

NCT04725994 2026-04-17

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer

87 enrolled

Gastrointestinal

Stomach Neoplasms

NCT05294731 2026-04-17

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

146 enrolled

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT05475925 2026-04-17

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas