Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Completed
709 enrolled
Rapid Autopsy and Procurement of Cancer Tissue
Completed
32 enrolled
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
Phase 2/3 Completed
159 enrolled 17 charts
Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative Persons
Phase 1/2 Completed
25 enrolled
Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy for Stage III Non-small Cell Lung Cancer
Phase 2 Completed
138 enrolled 42 charts
Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients
Phase 2 Completed
53 enrolled
Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors
Phase 1 Completed
47 enrolled
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
18 enrolled 12 charts
Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-Up Study
Completed
200 enrolled
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Completed
377 enrolled
Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk
Completed
40 enrolled
Genome Expression in Lymphoma, Leukemia and Multiple Myeloma
Completed
1,340 enrolled
Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China
Completed
9,759 enrolled
Breast Mammogram and Tissue Study
Completed
466 enrolled
Natural Killer Cells and Bortezomib to Treat Cancer
Phase 1 Completed
35 enrolled
Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study
Completed
1,892 enrolled
BRCA Mutations in Latinas
Completed
266 enrolled
Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
Completed
76 enrolled
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
Phase 1 Completed
16 enrolled
Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors
Phase 1 Completed
28 enrolled
Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies
Phase 1 Completed
134 enrolled
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Phase 1 Completed
27 enrolled
Prospective Screening for Patient-Specific Genotypes and Phenotypes That Influence Drug Dosing and Trial Selection in Cancer Patients
Completed
8 enrolled
A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients
Phase NA Completed
28 enrolled
Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias
Completed
10 enrolled
Cause of Familial Testicular Cancer
Completed
749 enrolled
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
Completed
178 enrolled
Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
Phase 2 Completed
47 enrolled
Developing the Family Map: Looking at Communal Coping
Completed
1,061 enrolled
Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Completed
313 enrolled
Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
Completed
17 enrolled
Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors
Phase 1 Completed
18 enrolled
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
Completed
272 enrolled
Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain
Completed
83 enrolled
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
20 enrolled 12 charts
Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers
Completed
119 enrolled
Nutrition Intervention Trials in Linxian Follow-up Study
Completed
32,902 enrolled
Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation
Phase 1 Completed
85 enrolled
Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins
Completed
130 enrolled
Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors
Phase 2 Completed
36 enrolled
Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases
Phase 2 Completed
344 enrolled 11 charts
Case-Control Study of Pesticides and Childhood Leukemia
Completed
629 enrolled
Risk Communication Within Mexican-American Families
Completed
498 enrolled
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Phase 1 Completed
10 enrolled
Esophageal Cancer in Northeastern Iran
Completed
50,045 enrolled
Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors
Phase 1 Completed
50 enrolled
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
23 enrolled 11 charts
Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
Completed
35 enrolled
Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome
Completed
273 enrolled
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Completed
1,387 enrolled