Clinical Trials

Melanoma, Neoplasm Metastasis

NCT05583708 2026-04-22

iPRRT

Phase 2 Recruiting

18 enrolled

Carcinoma, Merkel Cell

NCT05627245 2026-04-22

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

48 enrolled

DermatologicLymphoid

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT06585410 2026-04-22

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

369 enrolled

Skin Neoplasms

NCT06624644 2026-04-22

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

Phase 2/3 Recruiting

135 enrolled

Classical hematologyDermatologicSarcoma

Melanoma

NCT07005297 2026-04-22

Clinical Genetics Branch Eligibility Screening Survey

Not yet recruiting

1,000 enrolled

Cardiofaciocutaneous syndrome, Legius syndrome, Congenital Bone Marrow Failure Syndromes, Melanoma, Cutaneous Malignant, Chordoma, Fanconi Anemia, Melanoma, Neoplasms, Li-Fraumeni Syndrome, Pulmonary Blastoma, Costello Syndrome

NCT07144345 2026-04-22

Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

DermatologicOther neoplasm

160 enrolled

Precancerous Conditions, Skin Diseases, Keratosis, Actinic

NCT07144852 2026-04-22

Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities

DermatologicOther neoplasm

260 enrolled

Precancerous Conditions, Skin Diseases, Keratosis, Actinic

NCT07328516 2026-04-22

Natural History Study of Early Life Exposures in Agriculture (ELEA)

Enrolling by invitation

64,277 enrolled

BreastDermatologicGastrointestinalGenitourinaryOther hematologic neoplasm

Breast Neoplasms, Leukemia, Melanoma, Prostatic Neoplasms, Colorectal Neoplasms

NCT07401277 2026-04-22

Actinic Keratoses Treated With 5-fluorouracil Plus Aluminum

32 enrolled

Phase 1/2 Not yet recruiting

Keratosis, Actinic

NCT07472322 2026-04-22

ASTX727 & Retifanlimab-dlwr for Advanced Merkel Cell After Progression on Anti-PD-(L)1

31 enrolled

Phase 2 Not yet recruiting

Carcinoma, Merkel Cell

NCT07527325 2026-04-22

Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma

35 enrolled

Melanoma

NCT01590069 2026-04-21

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

DermatologicGenitourinarySarcoma

70 enrolled

Carcinoma, Renal Cell, Melanoma, Sarcoma, Osteosarcoma

NCT01604889 2026-04-21

A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma

Phase 1/2 Terminated

50 enrolled

870 enrolled 15 charts 1 FDA

Melanoma, Neoplasms, Skin Neoplasms

NCT01682083 2026-04-21

COMBI-AD

Phase 3 Completed

Melanoma, Neoplasms

NCT03076918 2026-04-21

Flexithera

Phase NA Completed

29 enrolled

Keratosis, Actinic

NCT03149029 2026-04-21

Abbreviated MAPK Targeted Therapy Plus Pembrolizumab in Melanoma

16 enrolled 10 charts

Melanoma

NCT05537740 2026-04-21

A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors

BreastDermatologicHead & NeckThoracic

129 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Recurrence, Triple Negative Breast Neoplasms

NCT06743126 2026-04-21

SUPRAME

360 enrolled

Melanoma, Cutaneous Malignant

NCT07092410 2026-04-21

SuRage-EB

Phase 4 Withdrawn

Melanoma

NCT07504796 2026-04-21

ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab

Phase 4 Recruiting

90 enrolled

Melanoma

NCT00923026 2026-04-20

Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

Enrolling by invitation

1,150 enrolled

DermatologicEndocrineNET

Adenocarcinoma, Carcinoma, Melanoma, Neuroendocrine Tumors

NCT02621021 2026-04-20

A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

Phase 2 Recruiting

170 enrolled

Melanoma, Skin Neoplasms

NCT03340506 2026-04-20

Dabrafenib and/or Trametinib Rollover Study

Phase 4 Recruiting

100 enrolled

CNSDermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Glioma, Lung Neoplasms, Melanoma

NCT04064424 2026-04-20

Cancer Prevention & Online Technologies

Phase NA Withdrawn

Skin Neoplasms

NCT04267861 2026-04-20

M7824 Related Adverse Effects in Adults With Cancer

Active not recruiting

232 enrolled

Neoplasms, Skin Neoplasms

NCT05068102 2026-04-20

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

DermatologicHead & NeckThoracic

14 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05294120 2026-04-20

A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma

38 enrolled

Carcinoma, Basal Cell

NCT05398640 2026-04-20

Expanded Access Program of AMTAGVI That is Out of Specification for Commercial Release

Available

Melanoma

NCT05571839 2026-04-20

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

DermatologicGastrointestinalOther solid neoplasmThoracic

41 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06066138 2026-04-20

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

DermatologicGastrointestinalSarcomaThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Sarcoma, Alveolar Soft Part, Small Cell Lung Carcinoma

NCT06150664 2026-04-20

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

BreastDermatologicHead & NeckLymphoidThoracic

85 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Hodgkin Disease, Melanoma, Triple Negative Breast Neoplasms

NCT06270706 2026-04-20

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

124 enrolled

Anus Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT06326411 2026-04-20

NST-628

230 enrolled

CNSDermatologic

Glioma, Melanoma, Neoplasms

NCT06568172 2026-04-20

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

DermatologicHead & NeckSarcoma

420 enrolled

Eyelid Squamous Cell Carcinoma

NCT07192471 2026-04-20

A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma

Phase 1 Not yet recruiting

72 enrolled

DermatologicLymphoid

Immune System Diseases, Lymphoma, Mycosis Fungoides, Neoplasms, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral

NCT07288203 2026-04-20

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma

100 enrolled

Melanoma, Skin Neoplasms

NCT07538960 2026-04-20

Epidemiology and Management of Cutaneous T-Cell Lymphoma at Hospital México, Costa Rica.

Not yet recruiting

350 enrolled

DermatologicLymphoid

Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT02713269 2026-04-17

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord