Clinical Trials

200 enrolled

Phase 2 Active not recruiting

MSI-H/dMMR Solid Tumors

NCT04123366 2026-04-22

MK-7339-007

300 enrolled

Phase 1/2 Active not recruiting

Solid Tumors

NCT04826341 2026-04-22

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

35 enrolled

HRD Cancer

NCT04959097 2026-04-22

rbliqbx

800 enrolled

Retinoblastoma

NCT05036291 2026-04-22

A Study of NB004 as Monotherapy or Combination Therapy in Patients With Advanced Solid Tumors

Phase 1 Terminated

25 enrolled

Advanced Solid Tumor

NCT06126276 2026-04-22

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

70 enrolled

Malignant Female Reproductive System Neoplasm

NCT06625593 2026-04-22

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

168 enrolled

Advanced Solid Tumor

NCT06779851 2026-04-22

SUMMIT-1

Phase 1 Terminated

20 enrolled

Advanced Solid Tumors

NCT07136779 2026-04-22

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

310 enrolled

Participants With Advanced Solid Tumor Malignancies

NCT07299747 2026-04-22

Clinical Trial of VBC103 in Patients With Advanced Malignant Solid Tumors

255 enrolled

Participants With Advanced Solid Tumor Malignancies

NCT07387068 2026-04-22

Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors

121 enrolled

GastrointestinalOther solid neoplasm

Advanced Solid Tumors

NCT07412613 2026-04-22

Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer

Phase 3 Recruiting

386 enrolled

Resectable Colon Cancer

NCT07489378 2026-04-22

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

4,000 enrolled

Phase 1/2 Not yet recruiting

Very Rare Tumors

NCT07545265 2026-04-22

SKB565 for Injection in Advanced Solid Tumors

180 enrolled

Phase NA Not yet recruiting

Advanced Solid Tumors

NCT07545291 2026-04-22

A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients

20 enrolled

Hematopoietic and Lymphatic System Neoplasm

NCT07545486 2026-04-22

ATOM-1st

Not yet recruiting

1,235 enrolled

Solid Tumor

NCT03710876 2026-04-21

INFINITE

Phase 3 Completed

53 enrolled 23 charts

Mesothelioma, Malignant

NCT05732831 2026-04-21

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

GastrointestinalOther solid neoplasmSarcomaThoracic

225 enrolled

Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT06480552 2026-04-21

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

240 enrolled

Advanced Solid Tumors

NCT06532565 2026-04-21

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

154 enrolled

Advanced Solid Tumors

NCT07204340 2026-04-21

TLN-372 in Advanced KRAS Mutant Solid Tumors

240 enrolled

KRAS Mutant Solid Tumors

NCT07246863 2026-04-21

Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

131 enrolled

Metastatic Non-Squamous Non-Small Cell Lung Cancer

NCT07346846 2026-04-21

A Study of BGM-2121 in Patients With Advanced Solid Tumors

35 enrolled

Phase 2 Active not recruiting

Advanced Solid Tumors

NCT07541001 2026-04-21

China Phase II

60 enrolled

Phase 1 Not yet recruiting

Advanced Malignant Solid Tumor

NCT07541534 2026-04-21

A Phase I Clinical Study of HLX316 in Participants With Advanced/Metastatic Solid Tumors

41 enrolled

Advanced/Metastatic Solid Tumors

NCT07541573 2026-04-21

Phase 1a/1b GTB-5550 in Advanced Solid Tumors

175 enrolled

Tri-specific Killer Engager

NCT01109394 2026-04-20

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

CNSGenitourinaryOther solid neoplasmSarcoma

6,035 enrolled

Kidney Neoplasms, Neoplasms, Neuroblastoma, Retinoblastoma, Sarcoma

NCT03739827 2026-04-20

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

10,000 enrolled

Malignant Solid Tumors

NCT03810339 2026-04-20

Toripalimab as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors

35 enrolled

Solid Tumor

NCT04431024 2026-04-20

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

800 enrolled

Mesothelioma

NCT04855656 2026-04-20

MYTHIC

464 enrolled

Phase 1 Active not recruiting

Advanced Solid Tumor

NCT05571839 2026-04-20

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

41 enrolled

DermatologicGastrointestinalOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06659341 2026-04-20

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

104 enrolled

Advanced Solid Tumors Harboring KRAS G12C Mutation

NCT06892379 2026-04-20

A Study of HS-20110 in Participants With Advanced Solid Tumors

475 enrolled

Solid Tumors

NCT07446855 2026-04-20

PARTHENON

180 enrolled

Phase 1 Not yet recruiting

Solid Tumours

NCT07538479 2026-04-20

NIVALIS

24 enrolled

Solid Tumors

NCT07539285 2026-04-20

A Study of HDM2024 in Participants With Advanced Solid Tumors

63 enrolled

Advanced Solid Tumors

NCT00242723 2026-04-17

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

GastrointestinalOther solid neoplasmThoracic

1,310 enrolled

Mesothelioma, Malignant, Esophageal Neoplasms, Lung Neoplasms

NCT02535312 2026-04-17

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

Phase 1/2 Active not recruiting

30 enrolled 15 charts

Mesothelioma, Malignant

NCT03317743 2026-04-17

Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors

Phase 1 Completed

32 enrolled

DermatologicHead & NeckOther solid neoplasmThoracic

Advanced Solid Tumors

NCT03881488 2026-04-17

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

Phase 1 Completed

100 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Melanoma, Mesothelioma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT04174716 2026-04-17

VASTUS

Phase 1/2 Completed

108 enrolled

Solid Tumors

NCT05960773 2026-04-17

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Phase 2 Suspended

9 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT06307795 2026-04-17

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

63 enrolled

Phase 2 Active not recruiting

Locally Advanced or Metastatic Solid Tumors

NCT06360588 2026-04-17

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G)

22 enrolled 9 charts

Malignant Solid Neoplasm

NCT06365840 2026-04-17

TMB-H

30 enrolled

TMB-H

NCT06581432 2026-04-17

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

430 enrolled

Solid Tumours

NCT06597721 2026-04-17

ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

210 enrolled

Advanced Solid Tumor

NCT07215039 2026-04-17

Improving Prison Health Equity Through Cancer Literacy and Screening Awareness in Florida

Enrolling by invitation

1,200 enrolled