Clinical Trials

150 enrolled

Sarcoma, Kaposi

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT07308886 2026-04-13

Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)

55 enrolled

Lymphoproliferative Disorders, Sarcoma, Kaposi

NCT04902443 2026-04-08

Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV

Phase 1 Recruiting

58 enrolled

Phase NA Active not recruiting

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT03737734 2026-04-06

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT06445166 2026-04-06

Propranolol for the Treatment of Kaposi Sarcoma in Adults

25 enrolled

Phase 1 Active not recruiting

Sarcoma, Sarcoma, Kaposi

NCT02659930 2026-04-01

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

62 enrolled

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT04303117 2026-03-25

PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Phase 1/2 Recruiting

80 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT05510908 2026-03-25

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

GastrointestinalGynecologicLymphoidSarcoma

460 enrolled 7 charts

AIDS-related Kaposi sarcoma, Acquired Immunodeficiency Syndrome, Anus Neoplasms, Uterine Cervical Neoplasms, Lymphoma, Neoplasms, Sarcoma, Kaposi, HIV Infections, Lymphoma, AIDS-Related

NCT06751355 2026-03-25

PRIME-KS

Phase 1 Active not recruiting

Sarcoma, Kaposi

NCT04514484 2026-03-23

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

8 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Kaposi, HIV Infections, Carcinoma, Medullary, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT05907759 2026-03-18

Daratumumab for Relapsed/Refractory Primary Effusion Lymphoma, Plasmablastic Lymphoma, and Multicentric Castleman Disease

28 enrolled

Phase NA Not yet recruiting

Multi-centric Castleman's Disease, Lymphoma, Non-Hodgkin, Sarcoma, Kaposi, Lymphoma, Primary Effusion

NCT06898203 2026-03-13

PRIME-KS

300 enrolled

Sarcoma, Kaposi

NCT04305691 2026-02-27

Trial of Ixazomib for Kaposi Sarcoma

41 enrolled

Sarcoma, Kaposi

NCT03300830 2026-02-05

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

280 enrolled

Acquired Immunodeficiency Syndrome, Castleman Disease, Immunologic Deficiency Syndromes, Sarcoma, Kaposi

NCT06480773 2026-02-05

KS-CARE

Active not recruiting

127 enrolled

Sarcoma, Kaposi

NCT04941274 2026-01-23

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Phase 1/2 Recruiting

86 enrolled

Phase 3 Not yet recruiting

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT05411237 2026-01-23

Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma

130 enrolled

Phase 2 Not yet recruiting

AIDS-related Kaposi sarcoma, Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT05797662 2026-01-23

A Study of Propranolol to Treat Kaposi Sarcoma

25 enrolled

Sarcoma, Kaposi

NCT05846724 2026-01-22

PULSAR

Phase 2 Withdrawn

GastrointestinalSarcomaThoracic

Sarcoma, Kaposi

NCT02408861 2026-01-21

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Terminated

79 enrolled 24 charts

Anus Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Sarcoma, Kaposi, HIV Infections

NCT04742387 2026-01-20

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Active not recruiting

40 enrolled

GynecologicLymphoidSarcoma

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Bone Diseases, Metabolic, Sarcoma, Kaposi, Lymphoma, Primary Effusion

NCT06004011 2026-01-15

ARROW

Phase NA Recruiting

4,100 enrolled

Uterine Cervical Neoplasms, Lymphoma, Non-Hodgkin, Sarcoma, Kaposi

NCT03077451 2025-12-17

Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

Phase 2 Completed

36 enrolled 13 charts

Sarcoma, Kaposi

NCT03886181 2025-12-08

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Phase NA Terminated

2 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05859074 2025-12-03

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Phase 1 Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Hemangiosarcoma, Melanoma, Neoplasm Metastasis, Neoplasms, Paget Disease, Extramammary, Sarcoma, Kaposi, Skin Neoplasms, Carcinoma, Merkel Cell, Adenocarcinoma, Sebaceous, Carcinoma, Skin Appendage

NCT03889899 2025-12-02

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.

Phase NA Recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04540588 2025-12-02

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

Phase NA Completed

2 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Recurrence, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT05663502 2025-07-17

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

GastrointestinalLymphoidOther hematologic neoplasmSarcoma

200 enrolled

Multi-centric Castleman's Disease, Plasmablastic Lymphoma, Anus Neoplasms, Lymphoma, Sarcoma, Kaposi, HIV Infections, Hematologic Neoplasms

NCT07066982 2025-07-15

BAH2573-103

Phase 1/2 Recruiting

60 enrolled

Lymphoma, Sarcoma, Sarcoma, Ewing, Sarcoma, Kaposi, Osteosarcoma, Sarcoma, Synovial

NCT03157167 2025-03-05

An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)

Phase 1 Completed

15 enrolled 12 charts

Sarcoma, Kaposi, HIV Infections

NCT04534127 2025-02-07

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia

Phase NA Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04028479 2024-12-18

ROOT

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidMyeloidNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

167 enrolled

Nasopharyngeal Carcinoma, Adenocarcinoma, Adrenal Gland Neoplasms, Anus Neoplasms, Appendiceal Neoplasms, Astrocytoma, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Carcinoid Tumor, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Adenoid Cystic, Esophageal Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liposarcoma, Liver Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Melanoma, Mesothelioma, Multiple Myeloma, Neoplasms, Multiple Endocrine Neoplasia, Neoplasms, Unknown Primary, Ovarian Neoplasms, Pancreatic Neoplasms, Parathyroid Neoplasms, Parotid Neoplasms, Penile Neoplasms, Pharyngeal Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Skin Neoplasms, Stomach Neoplasms, Sarcoma, Synovial, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Tongue Neoplasms, Ureteral Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Central Nervous System Neoplasms, Cholangiocarcinoma, Carcinoma, Small Cell, Neuroendocrine Tumors, Brain Stem Neoplasms, Gestational Trophoblastic Disease, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Phase 1 Completed

58 enrolled 17 charts

DermatologicGastrointestinalLymphoidSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT04893018 2024-06-27

NT-I7 for Kaposi Sarcoma in Patients With or Without HIV

Phase 1 Terminated

8 enrolled 14 charts

Phase EARLY_PHASE1 Completed

AIDS-related Kaposi sarcoma, Sarcoma, Kaposi, HIV Infections

NCT03316274 2024-06-25

Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma

12 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT02029430 2024-06-11

A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma

Phase 2 Completed

15 enrolled 9 charts

Acquired Immunodeficiency Syndrome, HIV Seropositivity, Neoplasms, Sarcoma, Sarcoma, Kaposi

NCT05081141 2024-05-07

HHV8 and Solid Organ Transplantation

250 enrolled

Castleman Disease, Sarcoma, Kaposi

NCT03993106 2024-05-02

A Study of sEphB4-HSA in Kaposi Sarcoma

65 enrolled

Sarcoma, Kaposi

NCT00339937 2024-03-22

Studies of Human Herpesvirus 8 and Kaposi's Sarcoma in Sicily

4,622 enrolled

Sarcoma, Kaposi

NCT00019188 2024-03-04

Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma

Phase 1/2 Completed

DermatologicSarcoma

AIDS-related Kaposi sarcoma, Neoplasms, Sarcoma, Kaposi, Skin Neoplasms

NCT05329792 2023-10-06

IntriNSiC

Phase 2 Unknown

70 enrolled

DermatologicSarcoma

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Sarcoma, Kaposi, Carcinoma, Merkel Cell

NCT03404297 2023-09-28

Compression Therapy for Leg Ulcers and Kaposi Sarcoma in Western Kenya

Phase NA Completed

Acquired Immunodeficiency Syndrome, Infections, Sarcoma, Kaposi

NCT00003008 2023-06-15

Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma

Phase 2 Completed

33 enrolled

AIDS-related Kaposi sarcoma, Sarcoma, Sarcoma, Kaposi

NCT01495598 2022-11-01

Pomalidomide for Kaposi Sarcoma in People With or Without HIV

Phase 1/2 Completed

28 enrolled 23 charts

Sarcoma, Kaposi

NCT00540566 2022-10-20

Optical Biopsy of Human Skin in Conjunction With Laser Treatment