Clinical Trials

Neuroblastoma

NCT04144023 2026-03-05

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

Phase 1 Recruiting

43 enrolled

Carcinoma, Intraductal, Noninfiltrating

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Phase 3 Recruiting

750 enrolled

Neuroblastoma, Ganglioneuroblastoma

NCT03794349 2026-02-18

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

94 enrolled 14 charts

Neuroblastoma

NCT03879694 2026-02-06

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

19 enrolled

Adenoma, Islet Cell

NCT05421897 2026-01-29

RAPID

11 enrolled

Neoplasms, Neuroblastoma

NCT05307835 2025-12-02

Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection

27 enrolled

Resectable Esophageal Cancer

NCT01134614 2025-11-25

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

245 enrolled 8 charts

Melanoma

NCT04385277 2025-10-27

Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)

41 enrolled 13 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00669734 2025-10-24

Vaccine Therapy and Sargramostim in Treating Patients With Pancreas Cancer That Cannot Be Removed By Surgery

18 enrolled

Locally Advanced Pancreatic Adenocarcinoma

NCT05455658 2025-10-24

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

33 enrolled

Triple Negative Breast Neoplasms

NCT06013618 2025-06-17

Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

Phase 2 Recruiting

120 enrolled

Neuroblastoma

NCT00661622 2025-05-16

Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF

53 enrolled 12 charts

Uveal Melanoma

NCT02334865 2025-05-11

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Other hematologic neoplasmPlasma cell

18 enrolled

Leukemia, Plasma Cell, Multiple Myeloma

NCT00436254 2025-04-06

Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer

66 enrolled

BreastGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms

NCT02780401 2024-09-19

WOKVAC

32 enrolled 13 charts

Breast Neoplasms

NCT05101356 2024-05-21

A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma

Phase 1/2 Recruiting

77 enrolled

Tumor-Agnostic

Adenocarcinoma, Neoplasm Metastasis

NCT02728102 2024-05-07

Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)

203 enrolled 25 charts

Plasma cell

Hematologic Diseases, Multiple Myeloma

NCT04197687 2023-12-18

TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery

Phase 2 Unknown

480 enrolled

Breast Neoplasms

NCT02636582 2023-12-05

Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer

43 enrolled 10 charts

Carcinoma, Intraductal, Noninfiltrating

NCT05344209 2023-11-09

LUNGVAC

Phase 2 Recruiting

138 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02484443 2023-10-26

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Classical hematologyMyeloidOther hematologic neoplasm

41 enrolled 15 charts

Sarcoma

Osteosarcoma

NCT00046930 2023-07-05

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Phase 3 Completed

449 enrolled 9 charts

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00071981 2023-06-28

Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma

175 enrolled 12 charts

Melanoma

NCT02620865 2023-05-15

BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer

Phase 1/2 Completed

2 enrolled 9 charts

Pancreatic Neoplasms

NCT02444546 2023-04-24

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

6 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioma, Medulloblastoma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT02593123 2023-01-23

Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis

LymphoidMyeloidOther hematologic neoplasmPlasma cell

31 enrolled 18 charts

Hodgkin Disease, Leukemia, Leukemia, Lymphoid, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell

NCT03012100 2023-01-13

Multi-epitope Folate Receptor Alpha Peptide Vaccine, GM-CSF, and Cyclophosphamide in Treating Patients With Triple Negative Breast Cancer

280 enrolled

Unilateral Breast Neoplasms, Breast Neoplasms, Inflammatory Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01767194 2022-10-24

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

73 enrolled 12 charts

Neuroblastoma, Ganglioneuroblastoma

NCT03645148 2021-11-16

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Pancreatic Cancer

7 enrolled

Pancreatic Neoplasms

NCT03662815 2021-11-16

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor

Phase 1 Unknown

30 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumor

NCT04810910 2021-11-16

Personalized Neoantigen Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Phase 1 Unknown

20 enrolled

Resectable Pancreatic Cancer

NCT00488592 2021-07-12

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

MyeloidOther hematologic neoplasm

10 enrolled 7 charts

Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute

NCT04864379 2021-04-28

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Phase 1 Unknown

30 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumor

NCT02677155 2021-03-01

Lymvac-2

10 enrolled

Lymphoid

Lymphoma, Follicular

NCT00064129 2020-07-30

Ipilimumab and Sargramostim in Treating Patients With Metastatic Prostate Cancer

42 enrolled

Genitourinary

Prostatic Neoplasms

NCT01989572 2020-07-07

Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery

Phase 3 Completed

815 enrolled 10 charts

Uveal Melanoma, Melanoma

NCT01363206 2020-03-19

GIPI

29 enrolled

Melanoma, Neoplasm Metastasis

NCT00514215 2020-03-05

Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer

8 enrolled 5 charts

GenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT00274287 2019-03-28

GM-CSF for Maintenance of Prostate Cancer for Patients Responding to Taxotere